猪传染性胃肠炎病毒（TGEV）纤突蛋白基因的核苷酸序列：与猫传染性腹膜炎病毒（FIPV）纤突蛋白序列的比较。
The nucleotide sequence of the peplomer gene of porcine transmissible gastroenteritis virus (TGEV): comparison with the sequence of the peplomer protein of feline infectious peritonitis virus (FIPV).
作者信息
Jacobs L, de Groot R, van der Zeijst B A, Horzinek M C, Spaan W
机构信息
Institute of Virology, Veterinary Faculty, State University, Utrecht, The Netherlands.
出版信息
Virus Res. 1987 Nov;8(4):363-71. doi: 10.1016/0168-1702(87)90008-6.
Abstract
The amino acid sequence of the peplomer protein of transmissible gastroenteritis virus (TGEV) has been derived from the cloned cDNA sequence. The gene encodes a protein of 1447 amino acids with a molecular weight of 159 574. Comparison with the primary structure of the peplomer protein of feline infectious peritonitis virus (FIPV) (de Groot et al., 1987b) revealed one domain, from amino acids 1 to 274, in which the nucleotide homology was 39%, whereas in the second domain (from residues 275 to 1447) the homology was 93%.
摘要
传染性胃肠炎病毒（TGEV）纤突蛋白的氨基酸序列已从克隆的cDNA序列推导得出。该基因编码一种由1447个氨基酸组成的蛋白质，分子量为159574。与猫传染性腹膜炎病毒（FIPV）纤突蛋白的一级结构比较（de Groot等人，1987b）显示，在第1至274位氨基酸的一个结构域中，核苷酸同源性为39%，而在第二个结构域（第275至1447位氨基酸）中，同源性为93%。
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