Soto-Penaloza David, Zaragozí-Alonso Regino, Penarrocha-Diago María, Penarrocha-Diago Miguel
Collaborating Lecturer, Master in Oral Surgery and Implant Dentistry, Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, Spain.
Dentist, Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, Spain.
J Clin Exp Dent. 2017 Mar 1;9(3):e474-e488. doi: 10.4317/jced.53613. eCollection 2017 Mar.
To systematically review the literature on the "all-on-four" treatment concept regarding its indications, surgical procedures, prosthetic protocols and technical and biological complications after at least three years in function.
The three major electronic databases were screened: MEDLINE (via PubMed), EMBASE, and the Cochrane Library of the Cochrane Collaboration (CENTRAL). In addition, electronic screening was made of the 'grey literature' using the System for Information on Grey Literature in Europe - Open Grey, covering the period from January 2005 up to and including April 2016.
A total of 728 articles were obtained from the initial screening process. Of these articles, 24 fulfilled the inclusion criteria. Methodological quality assessment showed sample size calculation to be reported by only one study, and follow-up did not include a large number of participants - a fact that may introduce bias and lead to misleading interpretations of the study results.
The all-on-four treatment concept offers a predictable way to treat the atrophic jaw in patients that do not prefer regenerative procedures, which increase morbidity and the treatment fees. The results obtained indicate a survival rate for more than 24 months of 99.8%. However, current evidence is limited due the scarcity of information referred to methodological quality, a lack of adequate follow-up, and sample attrition. Biological complications (e.g., peri-implantitis) are reported in few patients after a mean follow-up of two years. Adequate definition of the success / survival criteria is thus necessary, due the high prevalence of peri-implant diseases. All-on-four, all-on-4, tilted implants, dental prostheses, immediate loading.
系统回顾关于“all-on-four”治疗理念的文献,内容涉及该理念的适应证、手术操作、修复方案以及至少使用三年后的功能方面的技术和生物学并发症。
筛选了三个主要电子数据库:MEDLINE(通过PubMed)、EMBASE以及Cochrane协作网的Cochrane图书馆(CENTRAL)。此外,使用欧洲灰色文献信息系统——Open Grey对“灰色文献”进行了电子筛选,涵盖2005年1月至2016年4月期间。
初步筛选过程共获得728篇文章。其中,24篇符合纳入标准。方法学质量评估显示,只有一项研究报告了样本量计算,且随访未纳入大量参与者——这一事实可能会引入偏差并导致对研究结果的误导性解读。
“all-on-four”治疗理念为不倾向于采用增加发病率和治疗费用的再生手术的患者提供了一种可预测的治疗萎缩性颌骨的方法。获得的结果表明,超过24个月的生存率为99.8%。然而,由于方法学质量方面的信息稀缺、缺乏充分的随访以及样本流失,目前的证据有限。平均随访两年后,少数患者报告了生物学并发症(如种植体周围炎)。由于种植体周围疾病的高患病率,因此有必要对成功/生存标准进行充分定义。All-on-four、all-on-4、倾斜种植体、牙修复体、即刻加载