Tao Huaming, Wei Xiaoyi, Lin Xiuping, Zhou Xuefeng, Dong Junde, Yang Bin
b School of Traditional Chinese Medicine, Southern Medical University , Guangzhou , P. R. China.
c Key Laboratory of Plant Resources Conservation and Sustainable Utilization , South China Botanical Garden, Chinese Academy of Sciences , Guangzhou , P. R. China.
Nat Prod Res. 2017 Oct;31(19):2218-2222. doi: 10.1080/14786419.2017.1297442. Epub 2017 Mar 16.
Two new xanthone derivatives, penixanthones A (1) and B (2), together with three known compounds, aspenicillide (3), 1,5-dihydroxy-3-methoxy-7-methyl-anthracene-9,10-dione (4) and 1,2-indandiol (5), were isolated from the ethyl acetate extract of a culture of the fungus Penicillium sp. SYFz-1, which was separated from a mangrove soil sample. The structures of these compounds were elucidated by spectroscopic methods including NMR and mass spectrometry. The absolute configurations of penixanthones A (1) and B (2) were determined on the basis of electronic circular dichroism (ECD) data analysis.
从一株从红树林土壤样品中分离得到的青霉菌Penicillium sp. SYFz-1的培养物的乙酸乙酯提取物中，分离出两种新的氧杂蒽衍生物，penixanthones A（1）和B（2），以及三种已知化合物，曲霉内酯（3）、1,5-二羟基-3-甲氧基-7-甲基蒽醌-9,10-二酮（4）和1,2-茚二醇（5）。这些化合物的结构通过包括核磁共振和质谱在内的光谱方法得以阐明。基于电子圆二色光谱（ECD）数据分析确定了penixanthones A（1）和B（2）的绝对构型。
