Benacer Douadi, Zain Siti Nursheena Mohd, Ooi Peck Toung, Thong Kwai Lin
Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.
Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia.
Indian J Med Microbiol. 2017 Jan-Mar;35(1):124-128. doi: 10.4103/ijmm.IJMM_15_458.
Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n = 1; swine, n = 1) and environment (n = 2) were tested against six antibiotics. All the isolates were resistant to trimethoprim and sulphamethoxazole and had high MIC toward chloramphenicol (MIC90: 6.25 μg/ml). All except one environment isolate were sensitive to ampicillin, doxycycline and penicillin G.
钩端螺旋体病是一种由钩端螺旋体属致病性螺旋体引起的全球性人畜共患病。本研究的目的是评估从不同宿主分离得到的菌株的药敏性。对总共65株来自人类（n = 1）、人畜共患病（大鼠，n = 60；狗，n = 1；猪，n = 1）和环境（n = 2）的钩端螺旋体菌株进行了六种抗生素的药敏试验。所有菌株对甲氧苄啶和磺胺甲恶唑耐药，对氯霉素具有高最低抑菌浓度（MIC90：6.25μg/ml）。除一株环境菌株外，所有菌株对氨苄西林、多西环素和青霉素G敏感。
