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伊朗杂交薰衣草的化学成分与抗菌活性

Chemical Composition and Antibacterial Activity of Iranian Lavandula × hybrida.

作者信息

Bajalan Iman, Rouzbahani Razieh, Pirbalouti Abdollah Ghasemi, Maggi Filippo

机构信息

Young Researchers and Elite Club, Borujerd Branch, Islamic Azad University, Borujerd, Iran.

Department of Medicinal Plants, Shahrekord Branch, Islamic Azad University, P.O. Box 166, Shahrekord, Iran.

出版信息

Chem Biodivers. 2017 Jul;14(7). doi: 10.1002/cbdv.201700064. Epub 2017 Jun 13.

DOI:10.1002/cbdv.201700064
PMID:28306205
Abstract

Lavandin (Lavandula × hybrida) is an evergreen shrub and cultivated worldwide for its essential oil which possesses various biological activities. In this study, the essential oils were isolated from the leaves of ten lavandin populations in western Iran. The hydrodistilled essential oils were analyzed by GC-FID/MS. Results indicated significant differences (P ≤ 0.05) among the various populations for the main essential oil constituents. The major components from different populations were 1,8-cineole (31.64 - 47.94%), borneol (17.11 - 26.14%), and camphor (8.41 - 12.68%). In vitro antibacterial activity was evaluated against S. agalactiae, S. aureus, E. coli, and K. pneumoniae. The inhibition zones were in the range of 09.36 mm for S. aureus to 23.30 mm for E. coli. Results indicated that there was a significant correlation between essential oil composition and level of antibacterial efficacy expressed as inhibition zones.

摘要

醒目薰衣草(Lavandula × hybrida)是一种常绿灌木,因其具有多种生物活性的精油而在全球范围内种植。在本研究中,从伊朗西部的十个醒目薰衣草种群的叶子中分离出了精油。采用气相色谱 - 火焰离子化检测器/质谱联用仪(GC - FID/MS)对水蒸馏得到的精油进行了分析。结果表明,不同种群的主要精油成分存在显著差异(P≤0.05)。不同种群的主要成分是1,8 - 桉叶素(31.64% - 47.94%)、冰片(17.11% - 26.14%)和樟脑(8.41% - 12.68%)。对无乳链球菌、金黄色葡萄球菌、大肠杆菌和肺炎克雷伯菌进行了体外抗菌活性评估。抑菌圈范围从金黄色葡萄球菌的09.36毫米到大肠杆菌的23.30毫米。结果表明,精油成分与以抑菌圈表示的抗菌效果水平之间存在显著相关性。

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