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小鼠实验性病毒-细菌感染中的细胞现象。III. 体外接触病毒和细菌抗原后腹膜粒细胞吞噬活性的评估。

Cell phenomena in experimental viral-bacterial infections in mice. III. Estimation of the phagocytic activity of peritoneal granulocytes after in vitro contact with viral and bacterial antigens.

作者信息

Szydłowska T, Białek J, Denys A, Kowalska M

机构信息

Department of Medical Microbiology, Military Medical Academy, Lódź.

出版信息

Arch Immunol Ther Exp (Warsz). 1987;35(4):457-61.

PMID:2830858
Abstract

In the paper, the influence of in vitro contact of granulocytes with the antigen obtained from A/Scotland/74 and APR-8 influenza viruses as well as with staphylococcal anatoxine on phagocytic activity of granulocytes was examined. The results are given as phagocytic indices. In the group of animals infected with non-adapted influenza viruses the increase of phagocytosis was observed only in the first period of infection (on the 3rd and 6th day), whereas phagocytic index of granulocytes obtained from animals infected with adapted virus increased only on the 3rd day. In mixed infections, when granulocytes were contacted in vitro with viral as well as bacterial antigens, the insignificant increase of phagocytic indices was observed in the initial period of infection. On the other days of observation (on the 6th, 9th and 14th day) the obtained results approximated to values of phagocytic indices of granulocytes from the control group of animals.

摘要

在该论文中,研究了粒细胞在体外与从A/苏格兰/74和APR - 8流感病毒获得的抗原以及与葡萄球菌类毒素接触对粒细胞吞噬活性的影响。结果以吞噬指数表示。在感染未适应流感病毒的动物组中,仅在感染的第一阶段(第3天和第6天)观察到吞噬作用增强,而从感染适应病毒的动物获得的粒细胞吞噬指数仅在第3天增加。在混合感染中,当粒细胞在体外与病毒和细菌抗原接触时,在感染初期观察到吞噬指数略有增加。在观察的其他日子(第6天、第9天和第14天),获得的结果接近动物对照组粒细胞的吞噬指数值。

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