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对感染流感病毒的小鼠进行细胞免疫的体外研究。

In vitro studies on cellular immunity in mice infected with influenza virus.

作者信息

Denys A, Białek J, Grzybowski A

出版信息

Arch Immunol Ther Exp (Warsz). 1978;26(1-6):541-5.

PMID:749806
Abstract

Cell mediated immune response in mice infected with influenza A (Scotland) 73 (H3 N2) was studied by defining of the leukocyte migration inhibition, in vitro lymphocyte transformation and phagocytosis of S. aureus 209 P by the peritoneal exudate cells. It was found that the infection induces several changes in the reactivity of lymphoid cells which react with influenza antigens. The macrophage migration-inhibition occurs and it sustains until the 14th day. The mitogenic response to phytohemagglutinin weakens but, in the early period of infection the phagocytosis does not change but on the 14th day it also weakens.

摘要

通过测定白细胞迁移抑制、体外淋巴细胞转化以及腹膜渗出细胞对金黄色葡萄球菌209P的吞噬作用,研究了感染甲型流感病毒(苏格兰)73(H3N2)小鼠的细胞介导免疫反应。结果发现,该感染诱导了与流感抗原发生反应的淋巴细胞反应性的若干变化。巨噬细胞迁移抑制现象出现,并持续到第14天。对植物血凝素的促有丝分裂反应减弱,但在感染初期吞噬作用没有变化,不过在第14天其也减弱。

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