通过DNA杂交研究人乳头瘤病毒在异性恋和男同性恋伴侣中的性传播。
Sexual transmission of human papillomaviruses in heterosexual and male homosexual couples, studied by DNA hybridisation.
作者信息
Wickenden C, Hanna N, Taylor-Robinson D, Harris J R, Bellamy C, Carroll P, Malcolm A D, Coleman D V
机构信息
Department of Pathology, St Mary's Hospital Medical School, London.
出版信息
Genitourin Med. 1988 Feb;64(1):34-8. doi: 10.1136/sti.64.1.34.
Abstract
The prevalence of human papillomavirus (HPV) 6, 11, 16, and 18 in 36 heterosexual couples and seven male homosexual couples with genital warts was investigated for evidence of sexual transmission of genital HPV. The prevalence of virus type and number of copies of viral genome equivalents/cell in the lesions were assessed, and the factors influencing transmission analysed. Our results show that HPV 6 and, to a lesser extent, HPV 11 were the types most readily transmitted, and that transmission appears to depend on the copy number and the duration and frequency of exposure.
摘要
对36对异性恋伴侣和7对患有尖锐湿疣的男同性恋伴侣中的人乳头瘤病毒（HPV）6、11、16和18型进行了调查，以寻找生殖器HPV性传播的证据。评估了病变中病毒类型的流行率以及病毒基因组当量/细胞的拷贝数，并分析了影响传播的因素。我们的结果表明，HPV 6型以及在较小程度上的HPV 11型是最易传播的类型，而且传播似乎取决于拷贝数以及接触的持续时间和频率。
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