• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Effect of interferon on Vero cells persistently infected with Sendai virus compared to Vero cells persistently infected with SSPE virus.

作者信息

Crespi M, Chiu M N, Struthers J K, Schoub B D, Lyons S F

机构信息

National Institute for Virology, Sandringham, South Africa.

出版信息

Arch Virol. 1988;98(3-4):235-51. doi: 10.1007/BF01322172.

DOI:10.1007/BF01322172
PMID:2831857
Abstract

Persistent infections with Sendai and SSPE virus were established in Vero cells. Sequential passages of these cells were monitored by immunofluorescence and for their sensitivity to the antiviral and antiproliferative effects of interferon (IFN). The cells rapidly developed resistance to the antiviral effect of IFN as judged by the inability of IFN to inhibit the replication of exogenous Sindbis virus. This decrease was accompanied by a reduction in the induction of the 2'-5' oligo A synthetase. Both cell lines were resistant to the antiproliferative effect of IFN. A decrease or absence of IFN receptors on the surface of the cells was not found to be the cause of their resistance to IFN.

摘要

相似文献

1
Effect of interferon on Vero cells persistently infected with Sendai virus compared to Vero cells persistently infected with SSPE virus.
Arch Virol. 1988;98(3-4):235-51. doi: 10.1007/BF01322172.
2
Effect of interferon on Vero cells persistently infected with SSPE virus and lytically infected with measles virus.干扰素对持续感染亚急性硬化性全脑炎（SSPE）病毒并被麻疹病毒裂解感染的非洲绿猴肾（Vero）细胞的作用。
Arch Virol. 1986;90(1-2):87-96. doi: 10.1007/BF01314147.
3
The effect of interferon on cells persistently infected with HIV.
AIDS. 1989 Jan;3(1):33-6.
4
Interferon cures cells lytically and persistently infected with African swine fever virus in vitro.干扰素在体外可裂解性地和持续性地治愈被非洲猪瘟病毒感染的细胞。
Arch Virol. 1990;112(1-2):115-27. doi: 10.1007/BF01348989.
5
Possible involvement of virus-induced protein kinase in the antiviral state induced with interferon-gamma against Sindbis virus.病毒诱导的蛋白激酶可能参与γ干扰素诱导的针对辛德毕斯病毒的抗病毒状态。
J Interferon Res. 1989 Feb;9(1):23-34. doi: 10.1089/jir.1989.9.23.
6
Identification of a nonproductive, cell-associated form of measles virus by its resistance to inhibition by recombinant human interferon.通过重组人干扰素对其抑制作用的抗性鉴定出一种无活性的、细胞相关形式的麻疹病毒。
J Virol. 1987 Jun;61(6):1919-26. doi: 10.1128/JVI.61.6.1919-1926.1987.
7
The synergistic interaction of interferon types I and II leads to marked reduction in severe acute respiratory syndrome-associated coronavirus replication and increase in the expression of mRNAs for interferon-induced proteins.I型和II型干扰素的协同相互作用导致严重急性呼吸综合征相关冠状病毒复制显著减少，并使干扰素诱导蛋白的mRNA表达增加。
Intervirology. 2007;50(2):156-60. doi: 10.1159/000098242. Epub 2006 Dec 22.
8
Different kinetics of antiviral and anticellular activities between human recombinant and natural interferon-gamma arising from different receptor-binding properties.
Jpn J Cancer Res. 1986 Sep;77(9):946-55.
9
The interaction of interferon-alpha and -gamma: regulation of (2-5)A synthetase activity.α干扰素与γ干扰素的相互作用：（2-5）A合成酶活性的调节
Virology. 1988 Jul;165(1):87-94. doi: 10.1016/0042-6822(88)90661-7.
10
[Recombinant interferon-alpha suppression of Karelian fever virus replication in human blood cells].[重组干扰素-α对卡累利阿热病毒在人血细胞中复制的抑制作用]
Vopr Virusol. 2012 Mar-Apr;57(2):27-31.

引用本文的文献

1
Identification of interferon-resistant subpopulations in several strains of measles virus: positive selection by growth of the virus in brain tissue.几种麻疹病毒株中干扰素抗性亚群的鉴定：病毒在脑组织中生长的阳性选择
J Virol. 1990 Apr;64(4):1606-15. doi: 10.1128/JVI.64.4.1606-1615.1990.
2
Interferon cures cells lytically and persistently infected with African swine fever virus in vitro.干扰素在体外可裂解性地和持续性地治愈被非洲猪瘟病毒感染的细胞。
Arch Virol. 1990;112(1-2):115-27. doi: 10.1007/BF01348989.

本文引用的文献

1
Preparation of iodine-131 labelled human growth hormone of high specific activity.高比活度碘-131标记人生长激素的制备
Nature. 1962 May 5;194:495-6. doi: 10.1038/194495a0.
2
Persistent and lytic infections with SSPE virus: a comparison of the synthesis of virus-specific polypeptides.亚急性硬化性全脑炎病毒的持续性和溶解性感染：病毒特异性多肽合成的比较
J Gen Virol. 1981 Nov;57(Pt 1):191-7. doi: 10.1099/0022-1317-57-1-191.
3
An indirect radioimmunoassay for interferon.一种用于干扰素的间接放射免疫测定法。
J Virol Methods. 1982 Oct;5(2):93-100. doi: 10.1016/0166-0934(82)90086-6.
4
Identification of a major non-structural protein in the nuclei of Rift Valley fever virus-infected cells.
J Gen Virol. 1982 Jun;60(Pt 2):381-4. doi: 10.1099/0022-1317-60-2-381.
5
Growth regulation of melanoma cells by interferon and (2'-5')oligoadenylate synthetase.干扰素和（2'-5'）寡腺苷酸合成酶对黑色素瘤细胞生长的调节
Mol Cell Biol. 1983 May;3(5):780-6. doi: 10.1128/mcb.3.5.780-786.1983.
6
Binding of human interferon alpha to cells of different sensitivities: studies with internally radiolabeled interferon retaining full biological activity.人α干扰素与不同敏感性细胞的结合：对保留完全生物活性的内部放射性标记干扰素的研究
J Virol. 1983 Mar;45(3):1168-71. doi: 10.1128/JVI.45.3.1168-1171.1983.
7
Low interferon binding activity of two human cell lines which respond poorly to the antiviral and antiproliferative activity of interferon.
Virology. 1982 Oct 15;122(1):202-6. doi: 10.1016/0042-6822(82)90390-7.
8
Effects of exogenous interferon on L cells persistently infected with Sendai virus.外源性干扰素对被仙台病毒持续感染的L细胞的影响。
Arch Virol. 1984;80(1):33-45. doi: 10.1007/BF01315292.
9
Biochemistry of interferons and their actions.干扰素的生物化学及其作用
Annu Rev Biochem. 1982;51:251-82. doi: 10.1146/annurev.bi.51.070182.001343.
10
Monitoring of interferon therapy by assay of (2'--5') oligo-isoadenylate synthetase in human peripheral white blood cells.
J Interferon Res. 1981;1(4):587-94. doi: 10.1089/jir.1981.1.587.