School of Medical Sciences, University of New South Wales (UNSW) Sydney, Kensington, NSW 2052, Australia.
Trends Mol Med. 2017 Apr;23(4):293-295. doi: 10.1016/j.molmed.2017.02.008. Epub 2017 Mar 17.
Poor diets are associated with obesity and a decline in cognitive function. Flavonoids are plant compounds that have been associated with improved metabolic parameters in obesity and reversal of cognitive decline. Given that microbial flavonoid conversion is important for bioactivity, flavonoid-derived neuroactive compounds may be functionally crucial in the gut microbiome-brain axis.
不良饮食与肥胖和认知功能下降有关。类黄酮是植物化合物，与肥胖患者代谢参数的改善和认知能力下降的逆转有关。鉴于微生物转化类黄酮对于生物活性很重要，因此类黄酮衍生的神经活性化合物在肠道微生物群-大脑轴中可能具有重要的功能。
