莫拉克斯氏菌属作为类MCR多粘菌素耐药决定因素的潜在来源。
Moraxella Species as Potential Sources of MCR-Like Polymyxin Resistance Determinants.
作者信息
Kieffer Nicolas, Nordmann Patrice, Poirel Laurent
机构信息
Emerging Antibiotic Resistance, Medical and Molecular Microbiology Unit, Department of Medicine, University of Fribourg, Fribourg, Switzerland.
INSERM European Unit (IAME, France), University of Fribourg, Fribourg, Switzerland.
出版信息
Antimicrob Agents Chemother. 2017 May 24;61(6). doi: 10.1128/AAC.00129-17. Print 2017 Jun.
Abstract
Plasmid-mediated resistance to polymyxins mediated by the MCR-1/2 determinants has been reported in worldwide. Using PCR-based and cloning strategies, a series of spp. were screened for -like genes. spp. that are mainly animal pathogens but may also be human pathogens were identified as potential reservoirs of -like genes.
摘要
全球范围内已报道了由MCR - 1/2决定簇介导的质粒介导的对多粘菌素的耐药性。采用基于PCR的方法和克隆策略，对一系列菌株进行了类基因的筛选。主要作为动物病原体但也可能是人类病原体的菌株被确定为类基因的潜在储存库。
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