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2017 年欧洲癌症死亡率预测,重点关注肺癌。

European cancer mortality predictions for the year 2017, with focus on lung cancer.

机构信息

Department of Clinical Sciences and Community Health, Universitá degli Studi di Milano, Milan.

Department of Epidemiology, IRCCS-Istituto di Ricerche Farmacologiche 'Mario Negri', Milan, Italy.

出版信息

Ann Oncol. 2017 May 1;28(5):1117-1123. doi: 10.1093/annonc/mdx033.

Abstract

BACKGROUND

We predicted cancer mortality figures in the European Union (EU) for the year 2017 using most recent available data, with a focus on lung cancer.

MATERIALS AND METHODS

We retrieved cancer death certification data and population figures from the World Health Organisation and Eurostat databases. Age-standardized (world standard population) rates were computed for France, Germany, Italy, Poland, Spain, the UK and the EU overall in 1970-2012. We obtained estimates for 2017 by implementing a joinpoint regression model.

RESULTS

The predicted number of cancer deaths for 2017 in the EU is 1 373 500, compared with 1 333 400 in 2012 (+3%). Cancer mortality rates are predicted to decline in both sexes, reaching 131.8/100 000 men (-8.2% when compared with 2012) and 84.5/100 000 women (-3.6%). Mortality rates for all selected cancer sites are predicted to decline, except pancreatic cancer in both sexes and lung cancer in women. In men, pancreatic cancer rate is stable, in women it increases by 3.5%. Lung cancer mortality rate in women is predicted to rise to 14.6/100 000 in 2017 (+5.1% since 2012, corresponding to 92 300 predicted deaths), compared with 14.0/100 000 for breast cancer, corresponding to 92 600 predicted deaths. Only younger (25-44) women have favourable lung cancer trends, and rates at this age group are predicted to be similar in women (1.4/100 000) and men (1.2/100 000). In men lung cancer rates are predicted to decline by 10.7% since 2012, and falls are observed in all age groups.

CONCLUSION

European cancer mortality projections for 2017 confirm the overall downward trend in rates, with a stronger pattern in men. This is mainly due to different smoking prevalence trends in different generations of men and women. Lung cancer rates in young European women are comparable to those in men, confirming that smoking has the same impact on lung cancer in the two sexes.

摘要

背景

我们利用最新的可用数据预测了 2017 年欧盟(EU)的癌症死亡人数,重点关注肺癌。

材料和方法

我们从世界卫生组织和欧盟统计局数据库中检索了癌症死亡证明数据和人口数据。1970-2012 年,我们计算了法国、德国、意大利、波兰、西班牙、英国和欧盟整体的年龄标准化(世界标准人口)率。我们通过实施一个连接点回归模型来获得 2017 年的估计值。

结果

预计 2017 年欧盟的癌症死亡人数为 137.35 万,而 2012 年为 133.34 万(增加 3%)。预计男女两性的癌症死亡率均将下降,男性降至 131.8/100000(与 2012 年相比下降 8.2%),女性降至 84.5/100000(下降 3.6%)。除了男女两性的胰腺癌和女性肺癌之外,所有选定的癌症部位的死亡率预计都将下降。在男性中,胰腺癌的发病率保持稳定,而在女性中则增加了 3.5%。预计 2017 年女性肺癌死亡率将上升至 14.6/100000(比 2012 年上升 5.1%,对应预测死亡人数为 92300 人),而女性乳腺癌的死亡率为 14.0/100000,对应预测死亡人数为 92600 人。只有较年轻(25-44 岁)的女性肺癌有较好的趋势,且该年龄组女性(1.4/100000)和男性(1.2/100000)的发病率预计相似。2012 年以来,男性肺癌发病率预计下降 10.7%,且各年龄段均呈下降趋势。

结论

2017 年欧洲癌症死亡预测证实了总体发病率呈下降趋势,男性更为明显。这主要是由于不同世代的男性和女性吸烟流行趋势不同所致。欧洲年轻女性的肺癌发病率与男性相当,这证实了吸烟对两性肺癌的影响相同。

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