IEEE Rev Biomed Eng. 2017;10:136-161. doi: 10.1109/RBME.2017.2683520. Epub 2017 Mar 16.
Neural implants have emerged over the last decade as highly effective solutions for the treatment of dysfunctions and disorders of the nervous system. These implants establish a direct, often bidirectional, interface to the nervous system, both sensing neural signals and providing therapeutic treatments. As a result of the technological progress and successful clinical demonstrations, completely implantable solutions have become a reality and are now commercially available for the treatment of various functional disorders. Central to this development is the wireless power transfer (WPT) that has enabled implantable medical devices (IMDs) to function for extended durations in mobile subjects. In this review, we present the theory, link design, and challenges, along with their probable solutions for the traditional near-field resonant inductively coupled WPT, capacitively coupled short-ranged WPT, and more recently developed ultrasonic, mid-field, and far-field coupled WPT technologies for implantable applications. A comparison of various power transfer methods based on their power budgets and WPT range follows. Power requirements of specific implants like cochlear, retinal, cortical, and peripheral are also considered and currently available IMD solutions are discussed. Patient's safety concerns with respect to electrical, biological, physical, electromagnetic interference, and cyber security from an implanted neurotech device are also explored in this review. Finally, we discuss and anticipate future developments that will enhance the capabilities of current-day wirelessly powered implants and make them more efficient and integrable with other electronic components in IMDs.
在过去的十年中,神经植入物已成为治疗神经系统功能障碍和疾病的高效解决方案。这些植入物与神经系统建立了直接的、通常是双向的接口,既能感知神经信号,又能提供治疗。由于技术的进步和临床的成功示范,完全可植入的解决方案已经成为现实,并已商业化用于治疗各种功能障碍。无线能量传输 (WPT) 是这一发展的核心,它使植入式医疗设备 (IMD) 能够在移动的受试者中延长工作时间。在这篇综述中,我们介绍了传统近场感应耦合式 WPT、电容耦合短程 WPT 以及最近开发的超声、中场和远场耦合式 WPT 技术的理论、链路设计和挑战,以及它们可能的解决方案。根据功率预算和 WPT 范围对各种功率传输方法进行了比较。还考虑了特定植入物(如耳蜗、视网膜、皮质和外周)的功率要求,并讨论了当前可用的 IMD 解决方案。本文还探讨了患者对植入神经技术设备的电、生物、物理、电磁干扰和网络安全方面的安全问题。最后,我们讨论并预测了未来的发展,这将增强当前无线供电植入物的能力,并使它们更高效,与 IMD 中的其他电子组件更集成。