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医护人员中丙型肝炎病毒感染的风险及其与肝外表现的关联(综述)

The risk of HCV infection among health-care workers and its association with extrahepatic manifestations (Review).

作者信息

Garozzo Adriana, Falzone Luca, Rapisarda Venerando, Marconi Andrea, Cinà Diana, Fenga Concettina, Spandidos Demetrios A, Libra Massimo

机构信息

Section of Microbiology, Department of Biomedical and Biotechnological Sciences, University of Catania, I‑95124 Catania, Italy.

Section of General, Clinical and Oncological Pathology, Department of Biomedical and Biotechnological Sciences, University of Catania, I‑95123 Catania, Italy.

出版信息

Mol Med Rep. 2017 May;15(5):3336-3339. doi: 10.3892/mmr.2017.6378. Epub 2017 Mar 24.

Abstract

Health care workers (HCWs) are frequently exposed to different biological agents during their activities and are frequently monitored. Among these infectious agents, human hepatitis C (HCV) can infect HCWs. In this review article, the risk of HCV infection among HCWs is discussed along with extrahepatic HCV-related malignancies, such as non‑Hodgkin lymphoma. Accidental contamination, represented by percutaneous and mucocutaneous infections is the main risk factor for such infection. The compliance of the protection procedures, included in the current regulation for HCWs, is the most important issue to reduce the risk of pathogen infections that in turn may produce reduction of infection‑associated malignancies.

摘要

医护人员在其工作活动中经常接触不同的生物制剂,并且经常受到监测。在这些传染源中,丙型肝炎病毒(HCV)可感染医护人员。在这篇综述文章中,讨论了医护人员感染HCV的风险以及肝外HCV相关恶性肿瘤,如非霍奇金淋巴瘤。以经皮和黏膜皮肤感染为代表的意外污染是此类感染的主要危险因素。当前医护人员相关规定中所包含的防护程序的依从性,是降低病原体感染风险进而可能减少感染相关恶性肿瘤的最重要问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcd0/5428681/1ab765df2fbb/MMR-15-05-3336-g00.jpg

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