Pessôa Marina Gabriel, Paulino Bruno Nicolau, Mano Mario Cezar Rodrigues, Neri-Numa Iramaia Angélica, Molina Gustavo, Pastore Glaucia Maria
Laboratory of Bioflavors and Bioactive Compounds, Department of Food Science, Faculty of Food Engineering, University of Campinas, Monteiro Lobato St., 80, Cidade Universitária "Zeferino Vaz" Barão Geraldo, Campinas, São Paulo, CEP: 13803-862, Brazil.
Laboratory of Food Biotechnology - Food Engineering, Institute of Science and Technology, UFVJM, Diamantina, Minas Gerais, Brazil.
Appl Microbiol Biotechnol. 2017 May;101(9):3493-3511. doi: 10.1007/s00253-017-8255-z. Epub 2017 Mar 25.
Global demand for biotechnological products has increased steadily over the years. Thus, need for optimized processes and reduced costs appear as a key factor in the success of this market. A process tool of high importance is the direct or indirect use of enzymes to catalyze the generation of various substances. Also, obtaining aromas and pigments from natural sources has becoming priority in cosmetic and food industries in order to supply the demand from consumers to substitute synthetic compounds, especially when by-products can be used as starting material for this purpose. Species from Fusarium genera are recognized as promising sources of several enzymes for industrial application as well as biocatalysts in the production of aromas, pigments and second generation biofuels, among others. In addition, secondary metabolites from these strains can present important biological activities for medical field. In this approach, this review brings focus on the use of Fusarium sp. strains in biotechnological production of compounds of industrial interest, showing the most recent researches in this area, results obtained and the best process conditions for each case.
多年来，全球对生物技术产品的需求稳步增长。因此，优化工艺和降低成本的需求成为该市场成功的关键因素。一个非常重要的工艺工具是直接或间接使用酶来催化各种物质的生成。此外，从天然来源获取香料和色素已成为化妆品和食品行业的优先事项，以满足消费者替代合成化合物的需求，特别是当副产物可以用作此目的的起始原料时。镰刀菌属的物种被认为是几种工业应用酶以及香料、色素和第二代生物燃料等生产中的生物催化剂的有前途的来源。此外，这些菌株的次生代谢产物可能对医学领域具有重要的生物活性。在这种方法中，本综述聚焦于镰刀菌属菌株在工业感兴趣化合物的生物技术生产中的应用，展示了该领域的最新研究、获得的结果以及每种情况的最佳工艺条件。
