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心血管疾病患者恶性肿瘤的相关风险:证据和可能的机制。

Associated Risk of Malignancy in Patients with Cardiovascular Disease: Evidence and Possible Mechanism.

机构信息

Department of Cardiology, Shaare Zedek Medical Center, Jerusalem, Israel.

Department of Cardiology, Rabin Medical Center, Petach Tiqwa, Israel.

出版信息

Am J Med. 2017 Jul;130(7):780-785. doi: 10.1016/j.amjmed.2017.02.024. Epub 2017 Mar 24.

Abstract

Cardiovascular disease and malignancy are leading causes of morbidity and mortality. Increased risk of malignancy was identified in patients with cardiovascular disease, including patients with heart failure, heart failure after myocardial infarction, patients undergoing cardiac intervention, and patients after a thrombotic event. Common risk factors and biological pathways can explain this association and are explored in this review. Further research is needed to establish the causes of malignancy in this population and direct possible intervention.

摘要

心血管疾病和恶性肿瘤是发病率和死亡率的主要原因。心血管疾病患者,包括心力衰竭、心肌梗死后心力衰竭、接受心脏介入治疗的患者以及血栓事件后的患者,其恶性肿瘤风险增加。常见的危险因素和生物学途径可以解释这种关联,并在本综述中进行了探讨。需要进一步研究以确定该人群中恶性肿瘤的原因,并指导可能的干预措施。

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