Sahu Jyoti, Koley K M, Sahu B D
Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Anjora, Durg - 491 001, Chhattisgarh, India.
Department of Livestock Development, Dondi, Balod - 491 226, Chhattisgarh, India.
Vet World. 2017 Feb;10(2):221-226. doi: 10.14202/vetworld.2017.221-226. Epub 2017 Feb 19.
The study was conducted to evaluate the attribution of antibacterial and antioxidant activity of methanolic extract of toward its growth promoting effect in broiler birds.
A limit test was conducted for extract in Wistar albino rats. Phytochemical screening of methanolic extract of leaves of was carried out. In-vitro antibacterial activity was measured by disc diffusion method. 1-day-old Ven Cobb broiler birds (n=90) were randomly allocated into three groups consisting of three replicates with 10 birds in each group. The birds of group T1 (Control) received basal diet, whereas birds of group T2 (Standard) received an antibiotic (Lincomycin at 0.05% in feed). The birds of group T3 (Test) received extract (CSE) at 0.4 g/L in drinking water in addition to basal diet. The treatment was given to birds of all the groups for 6 weeks. Antioxidant activity of was determined in blood of broiler birds. Cumulative body weight gain, feed intake, feed conversion ratio (FCR), dressing percent, and organ weight factor were evaluated to determine growth performance in broiler birds.
Phytochemicals in were screened. Sensitivity to and resistant to and was observed in antibacterial activity test. At the end of 6 week, antioxidant activity reflected significantly (p≤0.05) lower level of erythrocyte malondialdehyde and higher levels of reduced glutathione (GSH) and GSH peroxidase in broiler birds of group T2 and T3 as compared to broiler of group T1. Mean cumulative body weight gain of birds of T2 and T3 were significantly (p≤0.05) higher as compared to T1. Mean FCR of birds of group T3 decreased significantly than group T1.
Supplementation of leaves extract at 0.4 g/L in drinking water improved growth performance in broiler birds due to its antimicrobial and antioxidant activity. Therefore, it could be used as an alternative to antibiotic growth promoter in poultry ration.
本研究旨在评估[提取物名称]甲醇提取物的抗菌和抗氧化活性对肉鸡生长促进作用的归因。
对[提取物名称]提取物在Wistar白化大鼠中进行了限度试验。对[植物名称]叶的甲醇提取物进行了植物化学筛选。采用纸片扩散法测定体外抗菌活性。将1日龄的文氏科布肉鸡（n = 90）随机分为三组，每组三个重复，每组10只鸡。T1组（对照组）的鸡只接受基础日粮，而T2组（标准组）的鸡只接受抗生素（饲料中添加0.05%的林可霉素）。T3组（试验组）的鸡只除接受基础日粮外，还在饮水中添加0.4 g/L的[提取物名称]提取物（CSE）。对所有组的鸡只进行6周的处理。测定了肉鸡血液中[提取物名称]的抗氧化活性。评估了累积体重增加、采食量、饲料转化率（FCR）、屠宰率和器官重量因子，以确定肉鸡的生长性能。
对[植物名称]中的植物化学物质进行了筛选。在[提取物名称]抗菌活性试验中观察到对[细菌名称1]敏感，对[细菌名称2]和[细菌名称3]耐药。在6周结束时，与T1组肉鸡相比，T2组和T3组肉鸡的红细胞丙二醛水平显著降低（p≤0.05），还原型谷胱甘肽（GSH）和GSH过氧化物酶水平显著升高。T2组和T3组鸡只的平均累积体重增加显著高于T1组（p≤0.05）。T3组鸡只的平均FCR显著低于T1组。
饮水中添加0.4 g/L的[植物名称]叶提取物可提高肉鸡的生长性能，这归因于其抗菌和抗氧化活性。因此，它可作为家禽日粮中抗生素生长促进剂的替代品。
