Conti Chiara, Mennitto Chiara, Di Francesco Giulia, Fraticelli Federica, Vitacolonna Ester, Fulcheri Mario
Department of Psychological, Health, and Territorial Sciences, University "G. d'Annunzio" of Chieti-Pescara , Chieti , Italy.
Department of Medicine and Aging, University "G. d'Annunzio" of Chieti-Pescara , Chieti , Italy.
Front Psychiatry. 2017 Mar 13;8:40. doi: 10.3389/fpsyt.2017.00040. eCollection 2017.
Diabetes mellitus (DM) is a chronic illness with impaired health-related quality of life and a high risk of psychiatric disorders. We carried out a systematic review analyzing the relationship between DM and suicide by providing a qualitative data synthesis of the studies.
We conducted, in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a systematic search of the literature in PubMed, Scopus, ISI Web of Science, PsycINFO, Google Scholar, and ScienceDirect. Search terms were "suicid*" combined with the Boolean "AND" operator with "diabetes."
The initial search identified 568 citations. A total of 17 research reports met the predefined inclusion criteria and were analyzed. DM was found to be significantly associated with a marked increase in suicidal behaviors and suicidal ideation (SI), especially in patients with depressive symptoms. Insulin therapy, DM of long duration, and unsatisfactory glycemic control were identified as risk factors for SI in Type 1 (T1DM) and Type 2 (T2DM).
Health-care professionals need to be aware of the higher suicidal risk in patient subgroups based on the clinical characteristics of DM; thus, patients with these characteristics warrant special attention. In this regard, clinical management should include efforts to manage emotional distress in DM care.
糖尿病（DM）是一种慢性疾病，会损害与健康相关的生活质量，且有患精神疾病的高风险。我们通过对研究进行定性数据综合分析，开展了一项系统评价，以分析糖尿病与自杀之间的关系。
我们按照系统评价和Meta分析的首选报告项目指南，在PubMed、Scopus、ISI科学网、PsycINFO、谷歌学术和ScienceDirect中对文献进行了系统检索。检索词为“suicid*”与布尔“AND”运算符和“diabetes”组合。
初步检索识别出568条引文。共有17篇研究报告符合预定义的纳入标准并进行了分析。发现糖尿病与自杀行为和自杀意念（SI）的显著增加显著相关，尤其是在有抑郁症状的患者中。胰岛素治疗、病程长的糖尿病以及血糖控制不佳被确定为1型糖尿病（T1DM）和2型糖尿病（T2DM）患者自杀意念的危险因素。
医护人员需要根据糖尿病的临床特征，意识到患者亚组中较高的自杀风险；因此，具有这些特征的患者值得特别关注。在这方面，临床管理应包括在糖尿病护理中努力管理情绪困扰。
