Wang Bo, Blin Thomas, Käkinen Aleksandr, Ge Xinwei, Pilkington Emily H, Quinn John F, Whittaker Michael R, Davis Thomas P, Ke Pu Chun, Ding Feng
Department of Physics and Astronomy, Clemson University, Clemson, SC, USA.
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.
Polym Chem. 2016 Dec 7;7(45):6875-6879. doi: 10.1039/C6PY01480A. Epub 2016 Sep 23.
To provide a molecular insight for guiding polymer coating in surface science and nanotechnology, here we examined the structures of brushed polyethylene glycol(bPEG)- and phosphorylcholine(bPC)-grafted iron oxide nanoparticles and analyzed their protein avoiding properties. We show bPC as an advantageous biomimetic alternative to PEG in rendering stealth nanostructures.
为了在表面科学和纳米技术中为聚合物涂层提供分子层面的见解以作指导，在此我们研究了接枝有刷状聚乙二醇（bPEG）和磷酸胆碱（bPC）的氧化铁纳米颗粒的结构，并分析了它们避免蛋白质吸附的特性。我们表明，在构建隐形纳米结构方面，bPC是一种比PEG更具优势的仿生替代物。
