Indwar Pallavi, Debnath Falguni, Sinha Arijit
Clinical Medicine Division, National Institute of Cholera and Enteric Diseases, Kolkata, West Bengal, India.
Epidemiology Division, National Institute of Cholera and Enteric Diseases, Kolkata, West Bengal, India.
J Family Med Prim Care. 2016 Oct-Dec;5(4):777-779. doi: 10.4103/2249-4863.201161.
Measles is affecting millions of people in the developing countries particularly in India with significant morbidity and responsible for thousands of death in spite of having a safe, effective, and cheap vaccine. Pulmonary complications account for 90% measles-related death. The objectives of this study were to describe age distribution, clinical features, complications, and clinical outcomes of measles cases in a referral infectious disease hospital of West Bengal.
We conducted a retrospective descriptive study including 584 patients and collected information from record section on demographics, clinical features, complications, and clinical outcomes using data abstraction form.
The mean age of 584 measles cases was 3.7 years (±1.2 years). The most common complication was pneumonia (149 cases) followed by diarrhea and encephalopathy. Very severe pneumonia occurred in 34 cases requiring intensive care out of which 13 patients died. The average duration of stay in the hospital was 5.7 days (±3.2 days). Surprisingly, 45 cases admitted to this hospital were <9 months of age with subsequent death in 5 cases.
Substantial number of measles cases was seen in zero to <9 months of age group and fatality due to complication was more among them.
尽管有安全、有效且廉价的疫苗,但麻疹仍在影响着发展中国家数以百万计的人,尤其是在印度,其发病率很高,导致数千人死亡。肺部并发症占麻疹相关死亡的90%。本研究的目的是描述西孟加拉邦一家转诊传染病医院中麻疹病例的年龄分布、临床特征、并发症及临床结局。
我们开展了一项回顾性描述性研究,纳入584例患者,并使用数据提取表从病历科室收集有关人口统计学、临床特征、并发症及临床结局的信息。
584例麻疹病例的平均年龄为3.7岁(±1.2岁)。最常见的并发症是肺炎(149例),其次是腹泻和脑病。34例发生非常严重的肺炎,需要重症监护,其中13例患者死亡。平均住院时间为5.7天(±3.2天)。令人惊讶的是,该医院收治的45例患者年龄小于9个月,其中5例随后死亡。
在0至小于9个月龄组中可见大量麻疹病例,且该年龄组因并发症导致的死亡率更高。