Erickson N, Boscheri A, Linke B, Huebner J
Comprehensive Cancer Center, Ludwig-Maximilian-University Clinic, Marchioninistr. 15, 81377, Munich, Germany.
Center for Prevention, Rehabilitation and Sports Medicine, Technical University of Munich Clinic at Rechts der Isar, Uptown München-Campus C, Georg-Brauchle-Ring 56/58, 3rd Floor, 80992, Munich, Germany.
Med Oncol. 2017 May;34(5):72. doi: 10.1007/s12032-017-0930-5. Epub 2017 Mar 28.
The efficacy and benefits of ketogenic diets (KD) have recently been gaining worldwide and remain a controversial topic in oncology. This systematic review therefore presents and evaluates the clinical evidence on isocaloric KD dietary regimes and reveals that evidence supporting the effects of isocaloric ketogenic dietary regimes on tumor development and progression as well as reduction in side effects of cancer therapy is missing. Furthermore, an array of potential side effects should be carefully considered before applying KD to cancer patients. In regard to counseling cancer patients considering a KD, more robust and consistent clinical evidence is necessary before the KD can be recommended for any single cancer diagnosis or as an adjunct therapy.
生酮饮食（KD）的功效和益处近来在全球范围内日益受到关注，并且在肿瘤学领域仍是一个有争议的话题。因此，本系统综述展示并评估了关于等热量生酮饮食方案的临床证据，结果显示，缺乏支持等热量生酮饮食方案对肿瘤发展、进展以及癌症治疗副作用减少有影响的证据。此外，在将生酮饮食应用于癌症患者之前，应仔细考虑一系列潜在的副作用。关于为考虑采用生酮饮食的癌症患者提供咨询，在能够推荐将生酮饮食用于任何单一癌症诊断或作为辅助治疗之前，需要更有力且一致的临床证据。
