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抑郁症、日常生活功能水平及疾病接纳度对帕金森病患者生活质量的影响:一项初步研究。

The influence of depression, level of functioning in everyday life, and illness acceptance on quality of life in patients with Parkinson's disease: a preliminary study.

作者信息

Rosińczuk Joanna, Kołtuniuk Aleksandra

机构信息

Department of Nervous System Diseases, Faculty of Health Science at Wrocław Medical University, Wrocław, Poland.

出版信息

Neuropsychiatr Dis Treat. 2017 Mar 21;13:881-887. doi: 10.2147/NDT.S132757. eCollection 2017.

DOI:10.2147/NDT.S132757
PMID:28356744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5367601/
Abstract

BACKGROUND

Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, and its incidence will increase as the global population ages. Due to the multitude of symptoms, this disease clearly has a significant impact on decreasing quality of life for those with PD. We aimed to evaluate the effect of selected variables on quality of life in people with idiopathic PD treated pharmacologically.

MATERIALS AND METHODS

This study was conducted among 50 patients with PD aged 47-85 years. The diagnostic survey method was applied to collect data with the use of the authors' questionnaire and standardized questionnaires, including, Parkinson's Disease Questionnaire (PDQ), Beck Depression Inventory, Instrumental Activities of Daily Living Scale, and Acceptance of Illness Scale. The results were statistically analyzed.

RESULTS

Analysis of the study material showed that people who were more self-reliant were characterized by lower intensity of depressive symptoms (=-0.567, =0), were more likely to accept their illness (=0.611, =0), and assessed quality of life better in each of the studied domains of the PDQ. Illness acceptance correlated with the occurrence of depressive symptoms (=-0.567, =0) and significantly affected quality of life.

CONCLUSION

Factors such as depression, disease acceptance, and functional capacity have a significant impact on the subjective assessment of quality of life in patients with PD. Evaluation of these factors should be taken into account in the therapeutic process, to minimize their negative impact on quality of life in patients with PD.

摘要

背景

帕金森病(PD)是仅次于阿尔茨海默病的第二常见神经退行性疾病,其发病率将随着全球人口老龄化而增加。由于症状众多,这种疾病显然对帕金森病患者的生活质量下降有重大影响。我们旨在评估所选变量对接受药物治疗的特发性帕金森病患者生活质量的影响。

材料与方法

本研究在50名年龄在47 - 85岁的帕金森病患者中进行。采用诊断性调查方法,使用作者自编问卷和标准化问卷收集数据,包括帕金森病问卷(PDQ)、贝克抑郁量表、日常生活活动能力量表和疾病接受度量表。对结果进行统计学分析。

结果

对研究材料的分析表明,更自立的人抑郁症状强度较低(=-0.567,=0),更有可能接受自己的疾病(=0.611,=0),并且在PDQ的每个研究领域中对生活质量的评估更好。疾病接受度与抑郁症状的发生相关(=-0.567,=0),并显著影响生活质量。

结论

抑郁、疾病接受度和功能能力等因素对帕金森病患者生活质量的主观评估有重大影响。在治疗过程中应考虑对这些因素进行评估,以尽量减少它们对帕金森病患者生活质量的负面影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f87/5367601/b86e26eb57cf/ndt-13-881Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f87/5367601/e4c15502ee50/ndt-13-881Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f87/5367601/b86e26eb57cf/ndt-13-881Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f87/5367601/e4c15502ee50/ndt-13-881Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f87/5367601/b86e26eb57cf/ndt-13-881Fig2.jpg

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