线粒体对细胞死亡的调控：一种系统发育保守的控制机制。
Mitochondrial regulation of cell death: a phylogenetically conserved control.
作者信息
Galluzzi Lorenzo, Kepp Oliver, Kroemer Guido
机构信息
Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, 75006 Paris, France.
INSERM, U1138, 75006 Paris, France.
出版信息
Microb Cell. 2016 Feb 23;3(3):101-108. doi: 10.15698/mic2016.03.483.
Mitochondria are fundamental for eukaryotic cells as they participate in critical catabolic and anabolic pathways. Moreover, mitochondria play a key role in the signal transduction cascades that precipitate many (but not all) regulated variants of cellular demise. In this short review, we discuss the differential implication of mitochondria in the major forms of regulated cell death.
线粒体对于真核细胞至关重要，因为它们参与关键的分解代谢和合成代谢途径。此外，线粒体在信号转导级联反应中起关键作用，这些反应引发了许多（但不是全部）细胞死亡的调节变体。在这篇简短的综述中，我们讨论了线粒体在主要形式的调节性细胞死亡中的不同作用。
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