Mocan Teodora, Matea Cristian T, Pop Teodora, Mosteanu Ofelia, Buzoianu Anca Dana, Puia Cosmin, Iancu Cornel, Mocan Lucian
Department of Nanomedicine, "Octavian Fodor" Gastroenterology Institute, 19-21 Croitorilor Street, Cluj-Napoca, Romania.
Department of Physiology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, Cluj-Napoca, Romania.
J Nanobiotechnology. 2017 Mar 31;15(1):25. doi: 10.1186/s12951-017-0260-y.
Pathogenic bacteria contribute to various globally important diseases, killing millions of people each year. Various fields of medicine currently benefit from or may potentially benefit from the use of nanotechnology applications, in which there is growing interest. Disease-related biomarkers can be rapidly and directly detected by nanostructures, such as nanowires, nanotubes, nanoparticles, cantilevers, microarrays, and nanoarrays, as part of an accurate process characterized by lower sample consumption and considerably higher sensitivity. There is a need for accurate techniques for pathogenic bacteria identification and detection to allow the prevention and management of pathogenic diseases and to assure food safety.
The focus of this review is on the current nanoparticle-based techniques for pathogenic bacterial identification and detection using these applications.
致病细菌导致各种全球范围内重要的疾病,每年造成数百万人死亡。目前医学的各个领域都受益于或可能潜在地受益于纳米技术应用,人们对其兴趣与日俱增。疾病相关的生物标志物可通过纳米结构快速、直接地检测出来,如纳米线、纳米管、纳米颗粒、悬臂梁、微阵列和纳米阵列,这是一个准确的过程,其特点是样品消耗少且灵敏度大大提高。需要有准确的技术来鉴定和检测致病细菌,以预防和管理致病疾病并确保食品安全。
本综述的重点是目前基于纳米颗粒的技术在这些应用中对致病细菌的鉴定和检测。