Allard Julie, Durand Céline, Anthony Samantha J, Dumez Vincent, Hartell David, Hébert Marie-Josée, West Lori J, Wright Linda, Fortin Marie-Chantal
Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Canada.; Canadian National Transplant Research Program, Canada.
Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Canada.
Transplant Direct. 2017 Jan 17;3(2):e127. doi: 10.1097/TXD.0000000000000639. eCollection 2017 Feb.
It is vitally important to seek input from key stakeholders to increase the quality and relevance of health-related research and accelerate its adoption into practice. Patients and caregivers have rarely been involved in setting research priorities in the transplantation and donation field. The objectives of this explorative study are: (i) to discuss research priorities within the Canadian National Transplant Research Program during a priority-setting exercise with patients, caregivers, organ donors and researchers and (ii) to compare the identified priorities with research published in 2 prestigious transplantation journals.
A pilot workshop attended by 10 patients and caregivers and 5 researchers was held in Montréal (Quebec, Canada) in August 2014 to identify research priorities. Priorities were identified using a thematic analysis of the workshop transcription conducted by multiple coders. These priorities were compared with the topics of research articles published in 2 major transplantation journals between 2012 and 2014.
The themes of the 10 research priorities identified by study participants were related to different research domains: social, cultural, and environmental health factors (4); biomedical or clinical (4); and research about health systems and services (2). 26.7% of the research articles published were related to the identified priorities. Thirteen percent looked at ways to improve graft survival and 8.5% looked at the development of tolerance, 2 priorities identified by participants. Fewer than 5% examined the other 8 research priorities identified as important by workshop participants.
This is the first study reporting patients' and researchers' priorities in the field of transplantation and donation in Canada. There is a discrepancy between topics that key stakeholders find important and research published in 2 major transplantation journals. The research priorities identified during our initial workshop will be validated through a national survey and workshop.
征求关键利益相关者的意见对于提高健康相关研究的质量和相关性，并加速其应用于实践至关重要。患者和护理人员很少参与移植和捐赠领域的研究优先级设定。本探索性研究的目的是：（i）在与患者、护理人员、器官捐赠者和研究人员进行优先级设定的过程中，讨论加拿大国家移植研究计划内的研究优先级；（ii）将确定的优先级与在2种著名移植期刊上发表的研究进行比较。
2014年8月在加拿大魁北克省蒙特利尔市举办了一个试点研讨会，10名患者和护理人员以及5名研究人员参加，以确定研究优先级。通过对由多名编码员进行的研讨会记录进行主题分析来确定优先级。将这些优先级与2012年至2014年间在2种主要移植期刊上发表的研究文章主题进行比较。
研究参与者确定的10个研究优先级主题与不同研究领域相关：社会、文化和环境健康因素（4个）；生物医学或临床（4个）；以及卫生系统和服务研究（2个）。已发表的研究文章中有26.7%与确定的优先级相关。13%关注提高移植物存活率的方法，8.5%关注耐受性的发展，这是参与者确定的2个优先级。不到5%的研究探讨了研讨会参与者确定为重要的其他8个研究优先级。
这是第一项报告加拿大移植和捐赠领域患者及研究人员优先级的研究。关键利益相关者认为重要的主题与在2种主要移植期刊上发表的研究之间存在差异。我们在初始研讨会上确定的研究优先级将通过全国性调查和研讨会进行验证。
