Chen Hanbo, Iascone Daniel Maxim, da Costa Nuno Maçarico, Lein Ed S, Liu Tianming, Peng Hanchuan
Allen Institute for Brain Science, Seattle, WA, USA.
Cortical Architecture Imaging and Discovery Laboratory, Department of Computer Science and Bioimaging Research Center, The University of Georgia, Athens, GA, USA.
Brain Inform. 2017 Sep;4(3):183-186. doi: 10.1007/s40708-017-0063-9. Epub 2017 Apr 1.
Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3D image sections. With its efficient algorithm and user-friendly interface, NeuronStitcher has been used successfully to reconstruct very large and complex human and mouse neurons.
从厚脑组织连续切片的三维图像堆栈中重建神经元非常耗时，并且常常成为高通量脑图谱项目的瓶颈。我们开发了NeuronStitcher，这是一套用于拼接在连续三维图像切片中重建的非重叠神经元片段的软件。凭借其高效的算法和用户友好的界面，NeuronStitcher已成功用于重建非常大且复杂的人类和小鼠神经元。
