Mun Sujeong, Kim Sujung, Bae Kwang-Ho, Lee Siwoo
Mibyeong Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 305-811, Republic of Korea.
Evid Based Complement Alternat Med. 2017;2017:9532073. doi: 10.1155/2017/9532073. Epub 2017 Mar 6.
Korean medicine (KM) patterns such as cold, heat, deficiency, and excess patterns have been associated with alterations of resting metabolic rate (RMR). However, the association of KM patterns with accurately measured body metabolic rate has not been investigated. Data on cold (CP), heat (HP), spleen-qi deficiency (SQDP), and kidney deficiency (KDP) patterns were extracted by a factor analysis of symptoms experienced by 954 participants. A multiple regression analysis was conducted to determine the association between KM patterns and RMR measured by an indirect calorimeter. The CP and SQDP scores were higher and the HP score was lower in women. The HP and SQDP scores decreased with age, while KDP scores increased with age. A multiple regression analysis revealed that CP and SQDP scores were negatively associated with RMR independently of gender and age, and the CP remained significantly and negatively associated with RMR even after adjustment for fat-free mass. The underlying pathology of CP and SQDP might be associated with the body's metabolic rate. Further studies are needed to investigate the usefulness of RMR measurement in pattern identification and the association of CP and SQDP with metabolic disorders.
寒、热、虚、实等中医证型与静息代谢率（RMR）的改变有关。然而，中医证型与精确测量的身体代谢率之间的关联尚未得到研究。通过对954名参与者所经历症状的因子分析，提取了寒证（CP）、热证（HP）、脾气虚证（SQDP）和肾虚证（KDP）的数据。进行多元回归分析以确定中医证型与通过间接测热法测量的RMR之间的关联。女性的CP和SQDP得分较高，而HP得分较低。HP和SQDP得分随年龄增长而降低，而KDP得分随年龄增长而增加。多元回归分析显示，CP和SQDP得分与RMR呈负相关，且独立于性别和年龄，即使在调整无脂肪体重后，CP与RMR仍保持显著负相关。CP和SQDP的潜在病理可能与身体的代谢率有关。需要进一步研究以探讨RMR测量在证型识别中的有用性以及CP和SQDP与代谢紊乱的关联。
