Centre for Research in Epidemiology and Population Health, Univ. Paris-Sud, UVSQ, INSERM U1018, Université Paris-Saclay, Villejuif, France.
Netherlands eScience Center, Amsterdam, The Netherland.
Sci Rep. 2017 Apr 3;8:45772. doi: 10.1038/srep45772.
Physical activity is key for successful ageing, but questions remain regarding the optimal physical activity pattern. We examined the cross-sectional association between physical activity and successful ageing using data on 3,749 participants (age range = 60-83years) of the Whitehall II study. The participants underwent a clinical assessment, completed a 20-item physical activity questionnaire, and wore a wrist-mounted accelerometer for 9 days. Successful ageing was defined as good cognitive, motor, and respiratory functioning, along with absence of disability, mental health problems, and major chronic diseases. Time spent in moderate-to-vigorous physical activity (MVPA) episodes assessed by accelerometer was classified as "short" (1-9.59 minutes) and "long" (≥10 minutes) bouts. Linear multivariate regression showed that successful agers (N = 789) reported 3.79 (95% confidence interval (CI): 1.39-6.19) minutes more daily MVPA than other participants. Accelerometer data showed this difference to be 3.40 (95% CI:2.44-4.35) minutes for MVPA undertaken in short bouts, 4.16 (95% CI:3.11-5.20) minutes for long bouts, and 7.55 (95% CI:5.86-9.24) minutes for all MVPA bouts lasting 1 minute or more. Multivariate logistic regressions showed that participants undertaking ≥150 minutes of MVPA per week were more likely to be successful agers with both self-reported (Odd Ratio (OR) = 1.29,95% (CI):1.09-1.53) and accelerometer data (length bout ≥1 minute:OR = 1.92, 95%CI:1.60-2.30). Successful agers practice more MVPA, having both more short and long bouts, than non-successful agers.
身体活动是成功老龄化的关键，但对于最佳身体活动模式仍存在疑问。我们使用来自 Whitehall II 研究的 3749 名参与者（年龄范围为 60-83 岁）的数据，研究了身体活动与成功老龄化之间的横断面关联。参与者接受了临床评估，完成了一份 20 项身体活动问卷，并佩戴了一个腕戴式加速度计 9 天。成功老龄化被定义为认知、运动和呼吸功能良好，且无残疾、心理健康问题和主要慢性疾病。通过加速度计评估的中等至剧烈体力活动（MVPA）时间分为“短”（1-9.59 分钟）和“长”（≥10 分钟）两个回合。线性多元回归显示，成功老龄化者（N=789）报告的日常 MVPA 比其他参与者多 3.79 分钟（95%置信区间[CI]：1.39-6.19）。加速度计数据显示，这一差异在短回合的 MVPA 中为 3.40 分钟（95% CI：2.44-4.35），长回合的 MVPA 中为 4.16 分钟（95% CI：3.11-5.20），所有持续 1 分钟或更长时间的 MVPA 回合中为 7.55 分钟（95% CI：5.86-9.24）。多元逻辑回归显示，每周进行≥150 分钟 MVPA 的参与者更有可能成为成功老龄化者，无论是自我报告（优势比[OR]：1.29，95% CI：1.09-1.53）还是加速度计数据（长度回合≥1 分钟：OR：1.92，95% CI：1.60-2.30）。成功老龄化者比非成功老龄化者进行更多的 MVPA，既有更多的短回合也有更多的长回合。
