Department of Dermatology, Peking Union Medical College Hospital, Beijing, China.
J Diabetes Investig. 2018 Jan;9(1):39-43. doi: 10.1111/jdi.12663. Epub 2017 May 24.
AIMS/INTRODUCTION: Psoriasis, a chronic autoimmune skin disorder, is believed to contribute to cardiovascular diseases and metabolic syndrome. Psoriasis's association with the components of metabolic syndrome has been reported previously. However, large-scale cross-sectional studies about psoriasis and metabolic syndrome are rare in China.
We assessed the prevalence of metabolic syndrome in Chinese psoriasis patients and controls.
A total of 859 psoriasis patients and 1,718 controls were recruited in an age- and sex-matched cross-sectional study. Metabolic syndrome occurred in 14.3% of the psoriasis patients as opposed to 10.0% of the control participants (P = 0.001). Psoriasis patients had a higher prevalence of overweight/obesity, hyperglycemia and dyslipidemia when compared with controls. Meanwhile, psoriasis patients with metabolic syndrome were older, and had an older age of onset and a longer disease duration when compared with those without metabolic syndrome.
The prevalence of metabolic syndrome is higher in the Chinese psoriatic population, which can favor cardiovascular events. The present study strengthens the value of treating psoriasis patients not only dealing with the skin lesions, and we suggest appropriate screening and relevant health education be carried out in the treatment of psoriasis patients.
目的/引言：银屑病是一种慢性自身免疫性皮肤病，被认为与心血管疾病和代谢综合征有关。银屑病与代谢综合征各组分之间的关系此前已有报道。然而，中国关于银屑病和代谢综合征的大规模横断面研究较为少见。
我们评估了中国银屑病患者和对照者中代谢综合征的患病率。
在一项年龄和性别匹配的横断面研究中，共纳入 859 例银屑病患者和 1718 例对照者。银屑病患者中代谢综合征的发生率为 14.3%，而对照组为 10.0%（P = 0.001）。与对照组相比，银屑病患者超重/肥胖、高血糖和血脂异常的患病率更高。同时，与无代谢综合征的患者相比，有代谢综合征的银屑病患者年龄更大，发病年龄更早，病程更长。
中国银屑病患者的代谢综合征患病率较高，这可能有利于心血管事件的发生。本研究进一步证实了治疗银屑病患者不仅要处理皮肤病变，还应在治疗银屑病患者时进行适当的筛查和相关的健康教育。
