Fernandes Brisa S, Williams Leanne M, Steiner Johann, Leboyer Marion, Carvalho André F, Berk Michael
IMPACT Strategic Research Centre, School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, VIC, 3216, Australia.
Barwon Health University Hospital, Geelong, Australia.
BMC Med. 2017 Apr 13;15(1):80. doi: 10.1186/s12916-017-0849-x.
Precision medicine is a new and important topic in psychiatry. Psychiatry has not yet benefited from the advanced diagnostic and therapeutic technologies that form an integral part of other clinical specialties. Thus, the vision of precision medicine as applied to psychiatry - 'precision psychiatry' - promises to be even more transformative than in other fields of medicine, which have already lessened the translational gap.
Herein, we describe 'precision psychiatry' and how its several implications promise to transform the psychiatric landscape. We pay particular attention to biomarkers and to how the development of new technologies now makes their discovery possible and timely. The adoption of the term 'precision psychiatry' will help propel the field, since the current term 'precision medicine', as applied to psychiatry, is impractical and does not appropriately distinguish the field. Naming the field 'precision psychiatry' will help establish a stronger, unique identity to what promises to be the most important area in psychiatry in years to come.
In summary, we provide a wide-angle lens overview of what this new field is, suggest how to propel the field forward, and provide a vision of the near future, with 'precision psychiatry' representing a paradigm shift that promises to change the landscape of how psychiatry is currently conceived.
精准医学是精神病学领域一个新的重要课题。精神病学尚未从构成其他临床专科不可或缺部分的先进诊断和治疗技术中受益。因此，应用于精神病学的精准医学愿景——“精准精神病学”——有望比其他医学领域带来更大变革，因为其他医学领域已经缩小了转化差距。
在此，我们描述“精准精神病学”及其多项意义如何有望改变精神病学格局。我们特别关注生物标志物以及新技术的发展如何使生物标志物的发现成为可能且及时。采用“精准精神病学”这一术语将有助于推动该领域发展，因为目前应用于精神病学的“精准医学”术语不切实际，无法恰当区分该领域。将该领域命名为“精准精神病学”将有助于为这个有望在未来数年成为精神病学最重要领域的学科确立更强大、独特的身份。
总之，我们从广角视角概述了这个新领域是什么，提出如何推动该领域向前发展，并展望了不久的将来，“精准精神病学”代表着一种范式转变，有望改变当前对精神病学的认知格局。
