完美碳青霉烯酶研究。
The Immaculate Carbapenemase Study.
机构信息
University of Louisville School of Medicine, Louisville, Kentucky, USA
出版信息
J Clin Microbiol. 2017 Jun;55(6):1608-1611. doi: 10.1128/JCM.00430-17. Epub 2017 Apr 12.
Abstract
Carbapenemase-producing organisms, or CPOs, are Gram-negative pathogens that produce a transmissible carbapenemase and are typically resistant to most (sometimes all) antibiotics. We now face a global CPO pandemic of high mortality. In this issue of the , Karlowsky et al. (J Clin Microbiol 55:1638-1649, 2017, https://doi.org/10.1128/JCM.02316-16) report the results of an extensive global surveillance study that provide much-needed information that enhances our understanding of carbapenemase-producing (CPE) and which will be valuable for the development of improved strategies for CPE control and therapy of infections.
摘要
产碳青霉烯酶的生物体（CPO）是革兰氏阴性病原体，可产生可传播的碳青霉烯酶，通常对大多数（有时是全部）抗生素具有耐药性。目前，我们正面临着高死亡率的全球产碳青霉烯酶流行。在本期的《临床微生物学杂志》（J Clin Microbiol 55:1638-1649, 2017, https://doi.org/10.1128/JCM.02316-16）中，Karlowsky 等人报告了一项广泛的全球监测研究的结果，这些结果提供了急需的信息，增强了我们对产碳青霉烯酶肠杆菌科（CPE）的理解，对于制定改进的 CPE 控制策略和感染治疗策略具有重要价值。
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