这是我们一直在等待的碳青霉烯酶检测方法吗？改良碳青霉烯酶灭活法的多中心评估。
Is This the Carbapenemase Test We've Been Waiting for? A Multicenter Evaluation of the Modified Carbapenem Inactivation Method.
机构信息
Department of Pathology and Laboratory Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Department of Pathology, Deaconess Health System, Evansville, Indiana, USA.
出版信息
J Clin Microbiol. 2017 Aug;55(8):2309-2312. doi: 10.1128/JCM.00538-17. Epub 2017 Jun 14.
Abstract
A plethora of phenotypic methods exist for the detection of carbapenemases; however, clinical laboratories have struggled for years with accurate, objective phenotypic detection of carbapenemase activity in In this issue of the , V. M. Pierce et al. (J Clin Microbiol 55:2321-2333, 2017, https://doi.org/10.1128/JCM.00193-17) report on a multicenter evaluation of the modified carbapenem inactivation method (mCIM). The high sensitivity, specificity, reproducibility, and ease of interpretation associated with the mCIM for will likely lead to its adoption by clinical laboratories.
摘要
有许多表型方法可用于检测碳青霉烯酶；然而，临床实验室多年来一直在努力准确、客观地检测碳青霉烯酶活性。在本期的《临床微生物学杂志》中，V. M. Pierce 等人（J Clin Microbiol 55:2321-2333, 2017, https://doi.org/10.1128/JCM.00193-17）报告了对改良碳青霉烯失活法（mCIM）的多中心评估。mCIM 用于检测碳青霉烯酶的高灵敏度、特异性、重现性和易于解释性，可能会导致临床实验室采用该方法。
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