Li Y C, Wang L Q, Yi L Y, Liu J H, Hu Y, Lu Y F, Wang M
Beijing Sport University.
Henan Sport Science Research Centre.
Biol Sport. 2017 Mar;34(1):39-43. doi: 10.5114/biolsport.2017.63731. Epub 2016 Dec 1.
The gene is one of the genes that have a potential influence on physical performance. Studies have shown that the genotype of is more prevalent in sprint athletes, while the genotype is more prevalent in endurance athletes. In swimming, both power and endurance related phenotypes are equally needed for swimmers to excel at the elite level. Therefore, the polymorphism may become a genetic marker for swimmers. The study aimed to examine the association of the genotype with the performance of elite middle-long distance (MLD) swimmers. The distributions of the genotype and allele were examined in a general population (206) and a group of elite MLD swimmers (160) in China by using PCR-RFLP and TOF. Compared with the general population, the elite MLD swimmers, especially the females, had a higher frequency of the genotype. The swimmers had a higher frequency of the allele than the general population. However, the difference was not statistically significant. After being stratified by performance, the difference of the allele frequency between the international master athletes and the general population was statistically significant. The elite MLD swimmers had a higher frequency of the genotype than the genotype compared with the general population. The polymorphism was associated with the performance of elite MLD swimmers in China. The SNP could be used as a biomarker for selecting elite MLD swimmers in China.
该基因是对身体表现有潜在影响的基因之一。研究表明，[基因名称]的基因型在短跑运动员中更为普遍，而[另一基因名称]的基因型在耐力运动员中更为普遍。在游泳项目中，力量和耐力相关的表型对于游泳运动员在精英水平上取得优异成绩同样重要。因此，[基因名称]多态性可能成为游泳运动员的遗传标记。本研究旨在探讨[基因名称]基因型与精英中长距离（MLD）游泳运动员成绩之间的关联。通过聚合酶链反应-限制性片段长度多态性分析（PCR-RFLP）和飞行时间质谱法（TOF），在中国的普通人群（206人）和一组精英MLD游泳运动员（160人）中检测了[基因名称]基因型和等位基因的分布。与普通人群相比，精英MLD游泳运动员，尤其是女性，[基因名称]基因型的频率更高。游泳运动员[基因名称]等位基因的频率高于普通人群。然而，差异无统计学意义。按成绩分层后，国际健将级运动员与普通人群之间[基因名称]等位基因频率的差异具有统计学意义。与普通人群相比，精英MLD游泳运动员[基因名称]基因型的频率高于[另一基因名称]基因型。[基因名称]多态性与中国精英MLD游泳运动员的成绩相关。单核苷酸多态性（SNP）[具体位点]可作为选拔中国精英MLD游泳运动员的生物标志物。
