Karass Michael, Grossniklaus Emily, Seoud Talal, Jain Sanjay, Goldstein Daniel A
New York Medical College, Valhalla, New York, USA
Emory University, Atlanta, Georgia, USA.
Oncologist. 2017 May;22(5):623-625. doi: 10.1634/theoncologist.2016-0237. Epub 2017 Apr 19.
Kaposi sarcoma inflammatory cytokine syndrome (KICS) is a newly-described condition affecting individuals who are HIV-positive and are infected with human herpesvirus 8 (HHV-8). This is a syndrome that in some ways mimics severe sepsis with associated acute respiratory distress syndrome, possibly requiring a ventilator and vasopressor support. However, unlike severe sepsis, antibiotics provide no benefit. Management of KICS has not been fully elucidated because of its high mortality rate. However, the syndrome has been successfully treated in some cases with immunomodulatory therapy. It is crucial for oncologists to be able to recognize this syndrome and to institute the appropriate therapy. 2017;22:623-625.
卡波西肉瘤炎性细胞因子综合征（KICS）是一种新描述的病症，影响HIV阳性且感染人疱疹病毒8（HHV - 8）的个体。这是一种在某些方面类似于伴有急性呼吸窘迫综合征的严重脓毒症的综合征，可能需要呼吸机和血管活性药物支持。然而，与严重脓毒症不同，抗生素并无益处。由于其高死亡率，KICS的管理尚未完全阐明。然而，该综合征在一些病例中已通过免疫调节疗法成功治疗。肿瘤学家能够识别这种综合征并进行适当治疗至关重要。2017年；22：623 - 625。
