Nanobioelectronics and Biosensor Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193, Barcelona, Spain.
ICREA, Pg. Lluís Companys 23, 08010, Barcelona, Spain.
Sci Rep. 2017 Apr 20;7(1):976. doi: 10.1038/s41598-017-01134-3.
Simple, inexpensive and rapid sensing systems are very demanded for a myriad of uses. Intrinsic properties of emerging paper-based analytical devices have demonstrated considerable potential to fulfill such demand. This work reports an easy-to-use, low cost, and disposable paper-based sensing device for rapid chemical screening with a smartphone readout. The device comprises luminescent graphene quantum dots (GQDs) sensing probes embedded into a nitrocellulose matrix where the resonance energy transfer phenomenon seems to be the sensing mechanism. The GQDs probes were synthesized from citric acid by a pyrolysis procedure, further physisorbed and confined into small wax-traced spots on the nitrocellulose substrate. The GQDs were excited by an UV LED, this, is powered by a smartphone used as both; energy source and imaging capture. The LED was contained within a 3D-printed dark chamber that isolates the paper platform from external light fluctuations leading to highly reproducible data. The cellulose-based device was proven as a promising screening tool for phenols and polyphenols in environmental and food samples, respectively. It opens up new opportunities for simple and fast screening of organic compounds and offers numerous possibilities for versatile applications. It can be especially useful in remote settings where sophisticated instrumentation is not always available.
简单、廉价且快速的感测系统对于各种用途都有很高的需求。新兴的基于纸张的分析器件的固有特性已经证明具有相当大的潜力来满足这种需求。本工作报道了一种易于使用、低成本且一次性的基于纸张的感测器件，可与智能手机读数配合进行快速化学筛选。该器件包含嵌入到硝酸纤维素基质中的发光石墨烯量子点 (GQD) 感测探针，其中共振能量转移现象似乎是感测机制。GQD 探针是通过热解程序从柠檬酸合成的，进一步物理吸附并限制在硝酸纤维素基质上的小蜡迹点中。GQD 由智能手机激发，智能手机既用作能源又用作成像捕获。LED 包含在 3D 打印的暗室中，该暗室将纸张平台与外部光线波动隔离开来，从而产生高度可重复的数据。基于纤维素的器件已被证明是环境和食品样品中酚类和多酚类物质的有前途的筛选工具。它为有机化合物的简单快速筛选开辟了新的机会，并为多功能应用提供了许多可能性。在复杂仪器并非总是可用的偏远环境中，它可能特别有用。
