鞭毛在幽门螺杆菌致病机制中的作用。
Role of Flagella in the Pathogenesis of Helicobacter pylori.
作者信息
Gu Haiying
机构信息
Medical School, Ningbo University, Ningbo, 315211, China.
出版信息
Curr Microbiol. 2017 Jul;74(7):863-869. doi: 10.1007/s00284-017-1256-4. Epub 2017 Apr 26.
Abstract
This review aimed to investigate the role of Helicobacter pylori flagella on the pathogenicity of this bacterium in humans. Helicobacter pylori is a flagellated pathogen that colonizes the human gastroduodenal mucosa and produces inflammation, and is responsible for gastrointestinal disease. Its pathogenesis is attributed to colonization and virulence factors. The primary function of H. pylori flagella is to provide motility. We believe that H. pylori flagella play an important role in the colonization of the gastrointestinal mucosa. Therefore, we reviewed previous studies on flagellar morphology and motility in order to explore the relationship between H. pylori flagella and pathogenicity. Further investigation is required to confirm the association between flagella and pathogenicity in H. pylori.
摘要
本综述旨在研究幽门螺杆菌鞭毛在该细菌对人类致病性中的作用。幽门螺杆菌是一种有鞭毛的病原体，可定殖于人类胃十二指肠黏膜并引发炎症，是胃肠道疾病的病因。其发病机制归因于定殖和毒力因子。幽门螺杆菌鞭毛的主要功能是提供运动性。我们认为幽门螺杆菌鞭毛在胃肠道黏膜定殖中发挥重要作用。因此，我们回顾了以往关于鞭毛形态和运动性的研究，以探讨幽门螺杆菌鞭毛与致病性之间的关系。需要进一步研究来证实幽门螺杆菌鞭毛与致病性之间的关联。
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