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来自肾茶的新二萜类化合物。

New Diterpenoids from Clerodendranthus spicatus.

作者信息

Li Ya-Mei, Xiang Bing, Li Xiao-Zheng, Yan Yong-Ming, Cheng Yong-Xian

机构信息

Yunnan University of Traditional Chinese Medicine, Kunming, 650504, People's Republic of China.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.

出版信息

Nat Prod Bioprospect. 2017 Jun;7(3):263-267. doi: 10.1007/s13659-017-0128-8. Epub 2017 May 3.

Abstract

Two new diterpenoids, neoorthosiphonones B and C (1 and 2), and one known diterpenoid, were isolated from the aerial parts of Clerodendranthus spicatus. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and X-ray crystallographic methods. No compound was found to inhibit fibronectin production at the concentration of 20 μM.

摘要

从肾茶地上部分分离得到两个新的二萜类化合物,新正丁香油酮B和C(1和2),以及一个已知的二萜类化合物。通过综合光谱分析和X射线晶体学方法确定了它们的结构,包括绝对构型。在20μM浓度下未发现有化合物抑制纤连蛋白的产生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f532/5481273/c0d3a9529978/13659_2017_128_Fig1_HTML.jpg

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