Probst Thomas, Pryss Rüdiger C, Langguth Berthold, Spiliopoulou Myra, Landgrebe Michael, Vesala Markku, Harrison Stephen, Schobel Johannes, Reichert Manfred, Stach Michael, Schlee Winfried
Georg-Elias-Müller Institute for Psychology, Georg-August University GöttingenGöttingen, Germany.
Institute of Databases and Information Systems, Ulm UniversityUlm, Germany.
Front Aging Neurosci. 2017 Apr 21;9:113. doi: 10.3389/fnagi.2017.00113. eCollection 2017.
For understanding the heterogeneity of tinnitus, large samples are required. However, investigations on how samples recruited by different methods differ from each other are lacking. In the present study, three large samples each recruited by different means were compared: = 5017 individuals registered at a self-help web platform for tinnitus (crowdsourcing platform Tinnitus Talk), = 867 users of a smart mobile application for tinnitus (crowdsensing platform TrackYourTinnitus), and = 3786 patients contacting an outpatient tinnitus clinic (Tinnitus Center of the University Hospital Regensburg). The three samples were compared regarding age, gender, and duration of tinnitus (month or years perceiving tinnitus; subjective report) using chi-squared tests. The three samples significantly differed from each other in age, gender and tinnitus duration ( < 0.05). Users of the TrackYourTinnitus crowdsensing platform were younger, users of the Tinnitus Talk crowdsourcing platform had more often female gender, and users of both newer technologies (crowdsourcing and crowdsensing) had more frequently acute/subacute tinnitus (<3 months and 4-6 months) as well as a very long tinnitus duration (>20 years). The implications of these findings for clinical research are that newer technologies such as crowdsourcing and crowdsensing platforms offer the possibility to reach individuals hard to get in contact with at an outpatient tinnitus clinic. Depending on the aims and the inclusion/exclusion criteria of a given study, different recruiting strategies (clinic and/or newer technologies) offer different advantages and disadvantages. In general, the representativeness of study results might be increased when tinnitus study samples are recruited in the clinic as well as via crowdsourcing and crowdsensing.
为了解耳鸣的异质性,需要大样本。然而,目前缺乏关于通过不同方法招募的样本之间差异的研究。在本研究中,对通过不同方式招募的三个大样本进行了比较:n1 = 5017名在耳鸣自助网络平台(众包平台Tinnitus Talk)注册的个体,n2 = 867名使用耳鸣智能移动应用程序的用户(众感知平台TrackYourTinnitus),以及n3 = 3786名联系门诊耳鸣诊所(雷根斯堡大学医院耳鸣中心)的患者。使用卡方检验对这三个样本在年龄、性别和耳鸣持续时间(感知耳鸣的月数或年数;主观报告)方面进行了比较。这三个样本在年龄、性别和耳鸣持续时间上存在显著差异(P < 0.05)。TrackYourTinnitus众感知平台的用户更年轻,Tinnitus Talk众包平台的用户女性比例更高,并且两种新技术(众包和众感知)的用户急性/亚急性耳鸣(<3个月和4 - 6个月)以及耳鸣持续时间非常长(>20年)的情况更为频繁。这些发现对临床研究的意义在于,众包和众感知平台等新技术提供了接触在门诊耳鸣诊所难以接触到的个体的可能性。根据特定研究的目的和纳入/排除标准,不同的招募策略(诊所和/或新技术)具有不同的优缺点。一般来说,当在诊所以及通过众包和众感知招募耳鸣研究样本时,研究结果的代表性可能会提高。