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小区域癌症数据的多元时空混合建模扩展

Extensions to Multivariate Space Time Mixture Modeling of Small Area Cancer Data.

作者信息

Carroll Rachel, Lawson Andrew B, Faes Christel, Kirby Russell S, Aregay Mehreteab, Watjou Kevin

机构信息

Department of Public Health Sciences, Medical University of South Carolina, 135 Cannon St, Charleston, SC 29425, USA.

Interuniversity Institute for Statistics and Statistical Bioinformatics, Hasselt University, 3500 Hasselt, Belgium.

出版信息

Int J Environ Res Public Health. 2017 May 9;14(5):503. doi: 10.3390/ijerph14050503.

DOI:10.3390/ijerph14050503
PMID:28486417
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5451954/
Abstract

Oral cavity and pharynx cancer, even when considered together, is a fairly rare disease. Implementation of multivariate modeling with lung and bronchus cancer, as well as melanoma cancer of the skin, could lead to better inference for oral cavity and pharynx cancer. The multivariate structure of these models is accomplished via the use of shared random effects, as well as other multivariate prior distributions. The results in this paper indicate that care should be taken when executing these types of models, and that multivariate mixture models may not always be the ideal option, depending on the data of interest.

摘要

口腔和咽癌,即便合在一起考虑,也是一种相当罕见的疾病。对肺癌、支气管癌以及皮肤黑素瘤实施多变量建模,可能会对口腔和咽癌得出更好的推断。这些模型的多变量结构是通过使用共享随机效应以及其他多变量先验分布来实现的。本文的结果表明,在执行这类模型时应谨慎,并且根据所关注的数据,多变量混合模型可能并不总是理想的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/24a712c59f74/ijerph-14-00503-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/063012ca1ff6/ijerph-14-00503-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/31c761c546fd/ijerph-14-00503-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/f32647134a00/ijerph-14-00503-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/c8b0ccd3fe81/ijerph-14-00503-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/24a712c59f74/ijerph-14-00503-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/063012ca1ff6/ijerph-14-00503-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/31c761c546fd/ijerph-14-00503-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/f32647134a00/ijerph-14-00503-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/c8b0ccd3fe81/ijerph-14-00503-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de1/5451954/24a712c59f74/ijerph-14-00503-g005.jpg

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本文引用的文献

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Spatiotemporal multivariate mixture models for Bayesian model selection in disease mapping.用于疾病地图绘制中贝叶斯模型选择的时空多元混合模型
Environmetrics. 2017 Dec;28(8). doi: 10.1002/env.2465. Epub 2017 Sep 25.
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Spatio-temporal Bayesian model selection for disease mapping.用于疾病地图绘制的时空贝叶斯模型选择
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Space-time variation of respiratory cancers in South Carolina: a flexible multivariate mixture modeling approach to risk estimation.
南非心血管疾病及部分危险因素的小范围差异及其与家庭和地区贫困的关系:捕捉南非的新趋势,以便更好地针对地方一级的干预措施。
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