Riahi Ryan R, Cohen Philip R
Dermatology, DermSurgery Associates, Sugar Land, USA.
Dermatologist, San Diego Family Dermatology, San Diego, USA.
Cureus. 2018 Nov 6;10(11):e3555. doi: 10.7759/cureus.3555.
Lichen planus is an inflammatory skin condition that can affect the hair, mucous membranes, nails, and skin. Cutaneous lichen planus typically presents as papules that are planar, polygonal, pruritic, and purple. Subtypes of lichen planus include actinic, annular, atrophic, eruptive, follicular, hypertrophic, inverse, linear, palmoplantar, pemphigoides, pigmentosus, ulcerative, vesiculobullous, and vulvovaginal. The various clinical presentations of lichen planus can mimic other dermatologic conditions. A 63-year-old woman, who presented with pruritic, hyperkeratotic plaques on the lower legs of two years duration, is described; her lesions were morphologically suggestive of verrucous lupus erythematosus. However, an examination also revealed purple papules on the wrists and white, reticulated patches on the bilateral buccal mucosa. Biopsies demonstrated lichenoid dermatitis while laboratory studies for systemic lupus erythematosus were negative. A correlation of the clinical presentation, pathology, and laboratory studies established a diagnosis of hypertrophic lichen planus. The clinical mimickers of hypertrophic lichen planus are reviewed and the therapeutic treatments for this condition discussed.
扁平苔藓是一种炎症性皮肤病，可累及毛发、黏膜、指甲和皮肤。皮肤扁平苔藓通常表现为扁平、多边形、瘙痒性的紫色丘疹。扁平苔藓的亚型包括光化性、环状、萎缩性、发疹性、毛囊性、肥厚性、反向性、线状、掌跖性、类天疱疮样、色素性、溃疡性、水疱大疱性和外阴阴道性。扁平苔藓的各种临床表现可模仿其他皮肤病。本文描述了一名63岁女性，其小腿出现瘙痒性角化过度斑块，病程长达两年；其皮损形态学提示疣状红斑狼疮。然而，检查还发现其手腕有紫色丘疹，双侧颊黏膜有白色网状斑片。活检显示为苔藓样皮炎，而系统性红斑狼疮的实验室检查为阴性。结合临床表现、病理和实验室检查结果，确诊为肥厚性扁平苔藓。本文回顾了肥厚性扁平苔藓的临床模仿者，并讨论了该病的治疗方法。
