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来自Hyrtios属的海洋海绵的生物活性天然产物。

Bioactive Natural Products of Marine Sponges from the Genus Hyrtios.

作者信息

Shady Nourhan Hisham, El-Hossary Ebaa M, Fouad Mostafa A, Gulder Tobias A M, Kamel Mohamed Salah, Abdelmohsen Usama Ramadan

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, Universities Zone, P.O. Box 61111 New Minia City, Minia, Egypt.

National Centre for Radiation Research & Technology, Egyptian Atomic Energy Authority, Ahmed El-Zomor St. 3, El-Zohoor Dist., P.O. Box 29 Nasr City, Cairo, Egypt.

出版信息

Molecules. 2017 May 11;22(5):781. doi: 10.3390/molecules22050781.

DOI:10.3390/molecules22050781
PMID:28492499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6153753/
Abstract

Marine sponges are known as a rich source for novel bioactive compounds with valuable pharmacological potential. One of the most predominant sponge genera is , reported to have various species such as , , , , and and a number of undescribed species. Members of the genus are a rich source of natural products with diverse and valuable biological activities, represented by different chemical classes including alkaloids, sesterterpenes and sesquiterpenes. This review covers the literature until June 2016, providing a complete survey of all compounds isolated from the genus with their corresponding biological activities whenever applicable.

摘要

海洋海绵被认为是具有宝贵药理潜力的新型生物活性化合物的丰富来源。最主要的海绵属之一是 ，据报道有多种物种，如 、 、 、 和 以及一些未描述的物种。该属成员是具有多样且有价值生物活性的天然产物的丰富来源，以包括生物碱、倍半萜内酯和倍半萜等不同化学类别为代表。本综述涵盖截至2016年6月的文献，尽可能全面地调查了从该属分离出的所有化合物及其相应的生物活性。

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