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马拉维布兰太尔地区三年(2008 - 2010年)的癌症发病率。

Three-year cancer incidence in Blantyre, Malawi (2008-2010).

作者信息

Chasimpha Steady J D, Parkin D Maxwell, Masamba Leo, Dzamalala Charles P

机构信息

Malawi Cancer Registry, Queen Elizabeth Hospital, Blantyre, Malawi.

CTSU, University of Oxford, United Kingdom.

出版信息

Int J Cancer. 2017 Aug 15;141(4):694-700. doi: 10.1002/ijc.30777. Epub 2017 May 25.

Abstract

In this paper, we present incidence rates of different cancers calculated for the population of Blantyre, Malawi for the period 2008-2010, using data from the Malawi Cancer Registry. Active methods were used for case finding, with standard checks for accuracy and validity performed in CanReg 4. During this 3-year period, a total of 3,711 cases were registered comprising 1,643 men (an estimated age-standardized incidence rate (ASR) of 169.8 per 100,000) and 2,068 women (ASR 238.7 per 10 ). Kaposi sarcoma (KS) was the most common cancer in men (40.5% of all cancers in men; ASR 54.0 per 10 ) while cervical cancer was the commonest in women (33.3%; ASR 88.6 per 10 ). The incidence rates for esophageal cancer remain one of the highest in the world (ASR 30.9 per 100,000 in men, 22.1 per 100,000 in women). Incidence of cancer of the prostate is relatively low in Blantyre (5.1%; ASR 16.4 per 10 ), compared with elsewhere in Africa. In childhood, the cancer spectrum is dominated by Burkitt lymphoma (32.5% ASR 90.9 per 10 ) followed by Wilms tumor (11.3%; ASR 35.9 per 10 ) and pediatric KS (11.0%; ASR 31.1 per 10 ). The overall percentage of cases with histological verification was 47.5%, a slight improvement from 42.4% in late 1990s also indicating successful case finding outside laboratories.

摘要

在本文中,我们利用马拉维癌症登记处的数据,呈现了2008 - 2010年期间马拉维布兰太尔人群中不同癌症的发病率。采用主动方法进行病例查找,并在CanReg 4中对准确性和有效性进行标准检查。在这3年期间,共登记了3711例病例,其中包括1643名男性(估计年龄标准化发病率(ASR)为每10万人169.8例)和2068名女性(ASR为每10万人238.7例)。卡波西肉瘤(KS)是男性中最常见的癌症(占男性所有癌症的40.5%;ASR为每10万人54.0例),而宫颈癌是女性中最常见的癌症(33.3%;ASR为每10万人88.6例)。食管癌的发病率仍然是世界上最高的之一(男性ASR为每10万人30.9例,女性为每10万人22.1例)。与非洲其他地区相比,布兰太尔前列腺癌的发病率相对较低(5.1%;ASR为每10万人16.4例)。在儿童时期,癌症谱以伯基特淋巴瘤为主(32.5%,ASR为每10万人90.9例),其次是肾母细胞瘤(11.3%;ASR为每10万人35.9例)和儿童KS(11.0%;ASR为每10万人31.1例)。组织学确诊病例的总体百分比为47.5%,比20世纪90年代末的42.4%略有提高,这也表明在实验室外成功找到了病例。

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