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2016 年 12 月在法国科西嘉岛出现的蓝舌病病毒血清型 4 的完整基因组序列。

Complete genome sequence of bluetongue virus serotype 4 that emerged on the French island of Corsica in December 2016.

机构信息

UMR 1161 ANSES/INRA/ENVA, Université Paris-Est ANSES Alfort, Maisons-Alfort, France.

Unit of Viral Genetics and Biosafety, Laboratory of Ploufragan, Anses, Ploufragan, France.

出版信息

Transbound Emerg Dis. 2018 Feb;65(1):e194-e197. doi: 10.1111/tbed.12660. Epub 2017 May 11.

Abstract

In November 2016, sheep located in the south of Corsica island exhibited clinical signs suggestive of bluetongue virus (BTV) infection. Laboratory analyses allowed to isolate and identify a BTV strain of serotype 4. The analysis of the full viral genome showed that all the 10 genomic segments were closely related to those of the BTV-4 present in Hungary in 2014 and involved in a large BT outbreak in the Balkan Peninsula. These results together with epidemiological data suggest that BTV-4 has been introduced to Corsica from Italy (Sardinia) where BTV-4 outbreaks have been reported in autumn 2016. This is the first report of the introduction in Corsica of a BTV strain previously spreading in eastern Europe.

摘要

2016 年 11 月,科西嘉岛南部的绵羊出现了疑似蓝舌病病毒(BTV)感染的临床症状。实验室分析允许分离和鉴定出一种血清型 4 的 BTV 株。对全病毒基因组的分析表明,所有 10 个基因组片段都与 2014 年匈牙利存在的 BTV-4 以及在巴尔干半岛发生的大规模 BT 爆发中的 BTV-4 密切相关。这些结果与流行病学数据表明,BTV-4 已从意大利(撒丁岛)传入科西嘉,2016 年秋季该岛报告了 BTV-4 爆发。这是 BTV 株首次传入科西嘉,此前该病毒株在东欧传播。

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