Hill Stephen, Galan M Carmen
School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK.
Beilstein J Org Chem. 2017 Apr 10;13:675-693. doi: 10.3762/bjoc.13.67. eCollection 2017.
Fluorescent carbon dots (FCDs) are an emerging class of nanomaterials made from carbon sources that have been hailed as potential non-toxic replacements to traditional semiconductor quantum dots (QDs). Particularly in the areas of live imaging and drug delivery, due to their water solubility, low toxicity and photo- and chemical stability. Carbohydrates are readily available chiral biomolecules in nature which offer an attractive and cheap starting material from which to synthesise FCDs with distinct features and interesting applications. This mini-review article will cover the progress in the development of FCDs prepared from carbohydrate sources with an emphasis on their synthesis, functionalization and technical applications, including discussions on current challenges.
荧光碳点(FCDs)是一类新兴的由碳源制成的纳米材料,被誉为传统半导体量子点(QDs)潜在的无毒替代品。特别是在活体成像和药物递送领域,因其具有水溶性、低毒性以及光稳定性和化学稳定性。碳水化合物是自然界中容易获得的手性生物分子,为合成具有独特特性和有趣应用的FCDs提供了一种有吸引力且廉价的起始材料。这篇综述文章将涵盖由碳水化合物源制备FCDs的发展进展,重点介绍其合成、功能化及技术应用,包括对当前挑战的讨论。