Tawfik Abeer Attia, Osman Mai Abdel Raouf
Dermatology and Laser at Dermatology Unit, Medical Laser Applications, National Institute Of Laser Enhanced Sciences (NIlES), Cairo University, Cairo, Egypt.
J Cosmet Dermatol. 2018 Feb;17(1):47-53. doi: 10.1111/jocd.12357. Epub 2017 May 14.
Hair is an essential part of a woman's appearance and attractiveness. This is reflected in the predominantly psychological morbidity that can be associated with female pattern hair loss. Platelet-rich plasma(PRP) has been used in numerous fields of medicine. Recently, PRP has received growing attention as a potential therapeutic tool for hair loss.
To evaluate the efficacy and safety of autologous platelet-rich plasma in the treatment of female pattern hair loss.
Thirty female patients with female pattern hair loss were randomly assigned to receive autologous PRP injection into a selected area, and another area was injected with normal saline as a placebo. Sessions were performed weekly for a maximum total of four sessions. Patients were followed up 6 months after the end of last session. The outcome was assessed both subjectively and objectively.
There was a statistical significant difference between PRP and placebo areas (P<.005) regarding both hair density and hair thickness as measured by a folliscope. The hair pull test became negative in PRP-injected areas in 25 patients (83%) with average number of three hairs. Global pictures showed a significant improvement in hair volume and quality together with a high overall patient satisfaction in PRP-injected sites, and these results were maintained during the 6-month follow- up.
Platelet-rich plasma injections can be regarded as an alternative for the treatment of female pattern hair loss with minimal morbidity and a low cost-to-benefit ratio.
头发是女性外貌和吸引力的重要组成部分。这体现在女性型脱发可能伴发的主要心理疾病中。富血小板血浆（PRP）已在众多医学领域得到应用。最近，PRP作为一种潜在的脱发治疗工具受到越来越多的关注。
评估自体富血小板血浆治疗女性型脱发的疗效和安全性。
30例女性型脱发患者被随机分配，在选定区域接受自体PRP注射，另一区域注射生理盐水作为对照。每周进行一次治疗，最多共进行四次。在最后一次治疗结束后6个月对患者进行随访。通过主观和客观评估结果。
用毛囊镜测量，PRP注射区域和对照区域在头发密度和头发厚度方面存在统计学显著差异（P<0.005）。在接受PRP注射的区域，25例患者（83%）的拔发试验转为阴性，平均掉发数量为三根。整体照片显示，PRP注射部位的头发量和发质有显著改善，患者总体满意度较高，且这些结果在6个月的随访期间得以维持。
富血小板血浆注射可被视为治疗女性型脱发的一种选择，其发病率极低，成本效益比也较低。
