Department of Surgical Sciences, Plastic and Reconstructive Surgery, University of Rome "Tor Vergata" School of Medicine, Rome, Italy.
Institute of Dermatology, F. Policlinico Gemelli IRCSS, Università Cattolica del Sacro Cuore, Rome, Italy.
Expert Opin Biol Ther. 2020 Mar;20(3):327-337. doi: 10.1080/14712598.2020.1724951. Epub 2020 Feb 14.
: A retrospective case-series study comparing autologous activated platelet-rich plasma (AA-PRP) versus autologous non-activated platelet-rich plasma (A-PRP) in hair re-growth was reported.: 90 patients, 63 males showing AGA in stage I-V by the Norwood-Hamilton scale and 27 females with AGA in stage I-III by the Ludwig scale, treated since 2013, were analyzed. 57 patients were treated with A-PRP injections and 33 patients were treated with AA-PRP in three sessions spaced 30 days average. Assessment of hair re-growth was evaluated in different weeks (Ws) after the treatment, summarized in four phases: T0, before the first infusion, T1 - 12 Ws, T2 - 23 Ws, T3 - 44 Ws, T4 - 58 Ws after the last treatment.: 12 Ws, 23 Ws, 44 Ws, and 58Ws after the last treatment, hair density measurements for patients treated with A-PRP and AA-PRP were 65 ± 5 and 28 ± 4 hairs/cm2 at T1, 28 ± 2 and 15 ± 3 hairs/cm2 at T2, 25 ± 3 and 14 ± 3 hairs/cm2 at T3, 23 ± 3 and 13 ± 3 hairs/cm at T4.: The effects of A-PRP and AA-PRP in hair re-growth during a long-term follow-up, was demonstrated.
一项回顾性病例系列研究比较了自体激活血小板富血浆（AA-PRP）与自体非激活血小板富血浆（A-PRP）在头发生长中的作用：90 例患者，63 例男性患者表现为诺伍德-汉密尔顿（Norwood-Hamilton）分级 I-V 期的 AGA，27 例女性患者表现为路德维希（Ludwig）分级 I-III 期的 AGA，自 2013 年开始接受治疗。其中 57 例患者接受 A-PRP 注射治疗，33 例患者接受 AA-PRP 治疗，3 次治疗间隔 30 天。治疗后不同周（Ws）评估头发生长情况，总结为四个阶段：T0，第一次输注前；T1，12 Ws；T2，23 Ws；T3，44 Ws；T4，最后一次治疗后 58 Ws。治疗后 12 Ws、23 Ws、44 Ws 和 58Ws，接受 A-PRP 和 AA-PRP 治疗的患者的头发密度测量值分别为 T1 时 65±5 和 28±4 根/cm2、T2 时 28±2 和 15±3 根/cm2、T3 时 25±3 和 14±3 根/cm2、T4 时 23±3 和 13±3 根/cm。证明了 A-PRP 和 AA-PRP 在头发生长中的长期作用。
