Department of Biotechnology, Punjabi University, Patiala-147002, India.
Department of Botany, Punjabi University, Patiala, 147 002, Punjab, India.
Phytother Res. 2017 Jul;31(7):980-1004. doi: 10.1002/ptr.5825. Epub 2017 May 17.
Phyllanthus niruri, a typical member of family Euphorbiaceae, is a small annual herb found throughout the tropical and subtropical regions of both hemispheres. The genus Phyllanthus has been used in traditional medicine for its wide range of pharmacological activities like antimicrobial, antioxidant, anticancer, antiinflammatory, antiplasmodial, antiviral, diuretic and hepatoprotective. This review summarizes the information about morphological, biochemical, ethanobotanical, pharmacological, biological and toxicological activities with special emphasis on mechanism of anticancer activity of P. niruri. Gaps in previous studies such as taxonomic inconsistency of P. niruri, novel phytochemicals and their therapeutic properties, especially mechanisms of anticancerous activity and market products available, have been looked into and addressed. Scientific information related to 83 phytochemicals (including many novel compounds detected recently by the authors) has been provided in a very comprehensive manner. Copyright © 2017 John Wiley & Sons, Ltd.
藤黄属植物，大戟科的一个典型成员，是一种小型一年生草本植物，分布于全球热带和亚热带地区。该属植物在传统医学中被广泛应用，具有多种药理学活性，如抗菌、抗氧化、抗癌、抗炎、抗疟原虫、抗病毒、利尿和保肝。本文综述了关于形态、生化、植物化学、药理学、生物学和毒理学活性的信息，特别强调了藤黄属植物的抗癌活性机制。本文还探讨并解决了之前研究中的一些空白，如藤黄属植物的分类学不一致、新型植物化学物质及其治疗特性，特别是抗癌活性的机制以及市场上现有的产品。本文以非常全面的方式提供了与 83 种植物化学物质（包括作者最近检测到的许多新型化合物）相关的科学信息。版权所有 © 2017 年约翰威立父子公司
