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用于小动物伽马射线成像应用的启用混合像素波形(HPWF)的碲化镉探测器。

Hybrid Pixel-Waveform (HPWF) Enabled CdTe Detectors for Small Animal Gamma-Ray Imaging Applications.

作者信息

Groll A, Kim K, Bhatia H, Zhang J C, Wang J H, Shen Z M, Cai L, Dutta J, Li Q, Meng L J

机构信息

Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, IL 61801 USA (primary:

Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114 USA.

出版信息

IEEE Trans Radiat Plasma Med Sci. 2017 Jan;1(1):3-14. doi: 10.1109/TNS.2016.2623807. Epub 2016 Nov 1.

Abstract

This paper presents the design and preliminary evaluation of small-pixel CdTe gamma ray detectors equipped with a hybrid pixel-waveform (HPWF) readout system for gamma ray imaging applications with additional discussion on CZT due to its similarity. The HPWF readout system utilizes a pixelated anode readout circuitry which is designed to only provide the pixel address. This readout circuitry works in coincidence with a high-speed digitizer to sample the cathode waveform which provides the energy, timing, and depth-of-interaction (DOI) information. This work focuses on the developed and experimentally evaluated prototype HPWF-CdTe detectors with a custom CMOS pixel-ASIC to readout small anode pixels of 350 μm in size, and a discrete waveform sampling circuitry to digitize the signal waveform induced on the large cathode. The intrinsic timing, energy, and spatial resolution were experimentally evaluated in this paper in conjunction with methods for depth of interaction (DOI) partitioning of the CdTe crystal. While the experimental studies discussed in this paper are primarily for evaluating HPWF detectors for small animal PET imaging, these detectors could find their applications for ultrahigh-resolution SPECT and other imaging modalities.

摘要

本文介绍了配备混合像素波形(HPWF)读出系统的小像素碲化镉γ射线探测器的设计和初步评估,用于γ射线成像应用,并因与碲锌镉(CZT)的相似性对其进行了额外讨论。HPWF读出系统采用像素化阳极读出电路,该电路设计为仅提供像素地址。该读出电路与高速数字化仪协同工作,对阴极波形进行采样,阴极波形提供能量、时间和相互作用深度(DOI)信息。这项工作聚焦于已开发并通过实验评估的原型HPWF-碲化镉探测器,其具有定制的互补金属氧化物半导体(CMOS)像素专用集成电路(ASIC),用于读出尺寸为350μm的小阳极像素,以及离散波形采样电路,用于将在大阴极上感应的信号波形数字化。本文结合碲化镉晶体相互作用深度(DOI)划分方法,对探测器的固有时间、能量和空间分辨率进行了实验评估。虽然本文讨论的实验研究主要用于评估用于小动物正电子发射断层扫描(PET)成像的HPWF探测器,但这些探测器也可用于超高分辨率单光子发射计算机断层扫描(SPECT)及其他成像模式。

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