Cai Liang, Lai Xiaochun, Shen Zengming, Chen Chin-Tu, Meng Ling-Jian
Department of Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana Champaign, Urbana, USA.
Department of Radiology, University of Chicago, Chicago, USA.
Nucl Instrum Methods Phys Res A. 2014 Jan 11;734(B):147-151. doi: 10.1016/j.nima.2013.08.080.
In this paper, we will report the development of an ultrahigh resolution MR-compatible SPECT system that can be operated inside a pre-existing clinical MR scanner for simultaneous dual-modality imaging of small animals. This system is constructed with 40 small-pixel CdTe detector modules assembled in a fully stationary ring SPECT geometry. We have experimentally demonstrated that this system is capable of providing an imaging resolution of <500 μm when operating inside MR scanners. We will report the design, construction of the MRI-compatible SPECT system, including the detector technology, collimator, system development and so on. The first imaging results obtained with this newly constructed SPECT system will also be reported.
在本文中，我们将报告一种超高分辨率的磁共振兼容单光子发射计算机断层显像（SPECT）系统的研发情况，该系统可在现有的临床磁共振扫描仪内运行，用于对小动物进行同步双模态成像。该系统由40个小像素碲化镉探测器模块构成，组装成完全固定的环形SPECT几何结构。我们通过实验证明，该系统在磁共振扫描仪内运行时能够提供小于500微米的成像分辨率。我们将报告该磁共振兼容SPECT系统的设计、构建情况，包括探测器技术、准直器、系统开发等。还将报告使用这一新构建的SPECT系统获得的首批成像结果。
