阿尔茨海默病临床试验参与的动机。
Motivators for Alzheimer's disease clinical trial participation.
机构信息
Graduate Center for Gerontology, College of Public Health, University of Kentucky, Lexington, KY, USA.
Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.
出版信息
Aging Clin Exp Res. 2018 Feb;30(2):209-212. doi: 10.1007/s40520-017-0771-2. Epub 2017 May 18.
BACKGROUND
Alzheimer's disease (AD) research progress is impeded due to participant recruitment challenges. This study seeks to better understand, from the perspective of individuals engaged in clinical trials (CTs), research motivations.
METHODS
Participants, or their caregivers, from AD treatment and prevention CTs were surveyed about research motivators.
RESULTS
The 87 respondents had a mean age of 72.2, were predominantly Caucasian, 55.2% were male, and 56.3% had cognitive impairment. An overwhelming majority rated the potential to help themselves or a loved one and the potential to help others in the future as important motivators. Relatively few respondents were motivated by free healthcare, monetary rewards, or to make others happy.
CONCLUSIONS
Recruitment efforts should focus on the potential benefit for the individual, their loved ones, and others in the future rather than free healthcare or monetary rewards.
背景
由于参与者招募的挑战，阿尔茨海默病（AD）的研究进展受到阻碍。本研究旨在从参与临床试验（CT）的个体的角度，更好地理解研究动机。
方法
对 AD 治疗和预防 CT 的参与者或其护理人员进行了关于研究动机的调查。
结果
87 名受访者的平均年龄为 72.2 岁，主要为白种人，55.2%为男性，56.3%有认知障碍。绝大多数人认为有潜力帮助自己或亲人，以及有潜力帮助未来的他人是重要的动机。相对较少的受访者受免费医疗保健、金钱奖励或让他人快乐的动机驱使。
结论
招募工作应侧重于个人、他们的亲人以及未来他人的潜在利益，而不是免费医疗保健或金钱奖励。
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